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Phase 2
A Phase 2, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, PK, and Efficacy of Vimseltinib in Adults With Active Chronic GVHD After Failure of Prior Systemic Therapy
The purpose of this study is to determine if vimseltinib is safe, tolerable and works effectively to treat adults with active moderate to severe cGVHD. Partici…
Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLCNCT06619561
Phase 2
Phase II Randomized Study of Ruxolitinib vs Prednisone as First-Line Therapy for Chronic Graft vs Host Disease Needing Systemic Therapy
Allogeneic transplant is potentially curative for hematological malignancies but its use is limited by the development of GVHD. Ruxolitinib now has FDA approva…
Chronic Graft-versus-host Disease (cGVHD)
H. Lee Moffitt Cancer Center and Research InstituteNCT06660355