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7 recruiting studies matching your filters

Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta

The goals of this clinical study are to first learn more about safety and dosing of the study drug GS-4321 in healthy participants. The study will then learn a…

Chronic Hepatitis Delta

Estimated

~$10 – $7,500

Gilead SciencesNCT07096193

Phase 3

A Multicenter, Randomized, Controlled, Open-label, Phase III Study to Assess Efficacy and Safety of Libevitug Injection in Participants With Chronic Hepatitis Delta Virus Infection (D-clear Study)

This is an international, multicenter, randomized, controlled, open-label Phase III trial. It will evaluate the efficacy and safety of libevitug in participant…

Chronic Hepatitis D Infection

Estimated

~$10 – $7,500

Huahui HealthNCT07499544

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for th…

CancerLiver CirrhosisChronic Hepatitis+4 more

Estimated

~$10 – $1,125

Helio GenomicsNCT05181826

Adaptability of an Undetectable = Untransmissible Model for HBV: Are Suppressed Viral Levels in the Serum Consistent Across Body Fluid Reservoirs?

Persons with chronic hepatitis B (HBV) infection and active viremia are infectious and may transmit virus to others through blood/body fluid exposure. Immune t…

Chronic Hepatitis bViremia

Estimated

~$10 – $1,125

NYU Langone HealthNCT07449091

Phase 2

Pilot Study to Evaluate Intrahepatic and Peripheral Responses to Small Interfering RNA, Imdusiran (AB-729), Among People With Chronic Hepatitis B

The goal of this clinical trial is to learn about the action of Imdusiran (AB-729) in the liver of people with chronic hepatitis B. The main questions it aims …

Chronic Hepatitis B

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT06154278

Phase 1

Augmentation of Humoral Immunity Using Toll-Like Receptor (TLR) 9 Adjuvanted HBV Surface Antigen to Enhance Anti-HBSAg Response

The goal of this clinical trial is to learn if HEPLISAV-B, a vaccine that is approved to prevent hepatitis B infection in people that are not already infected,…

Hepatitis BChronic Hepatitis B

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT04843852

Phase 1

A Phase 1 Non-Randomized, Open-Label, Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function

This is a Phase 1 non-randomized, open-label, single-dose study of pevifoscorvir sodium (also known as ALG-000184) in participants with severe renal impairment…

Chronic Hepatitis B Infection

Estimated

~$10 – $8,750

Aligos TherapeuticsNCT07342881