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7 recruiting studies matching your filters

A Pilot Study of the Combination of VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B

Background: Chronic hepatitis B virus (HBV) infection affects 292 million people worldwide; 887,000 die each year from cirrhosis, liver cancer, and related is…

Chronic Hepatitis B

Estimated

~$10 – $5,625

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT06092333

Phase 1

Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta

The goals of this clinical study are to first learn more about safety and dosing of the study drug GS-4321 in healthy participants. The study will then learn a…

Chronic Hepatitis Delta

Estimated

~$10 – $7,500

Gilead SciencesNCT07096193

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for th…

CancerLiver CirrhosisChronic Hepatitis+4 more

Estimated

~$10 – $1,125

Helio GenomicsNCT05181826

Adaptability of an Undetectable = Untransmissible Model for HBV: Are Suppressed Viral Levels in the Serum Consistent Across Body Fluid Reservoirs?

Persons with chronic hepatitis B (HBV) infection and active viremia are infectious and may transmit virus to others through blood/body fluid exposure. Immune t…

Chronic Hepatitis bViremia

Estimated

~$10 – $1,125

NYU Langone HealthNCT07449091

Phase 2

Pilot Study to Evaluate Intrahepatic and Peripheral Responses to Small Interfering RNA, Imdusiran (AB-729), Among People With Chronic Hepatitis B

The goal of this clinical trial is to learn about the action of Imdusiran (AB-729) in the liver of people with chronic hepatitis B. The main questions it aims …

Chronic Hepatitis B

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT06154278

Phase 1

Augmentation of Humoral Immunity Using Toll-Like Receptor (TLR) 9 Adjuvanted HBV Surface Antigen to Enhance Anti-HBSAg Response

The goal of this clinical trial is to learn if HEPLISAV-B, a vaccine that is approved to prevent hepatitis B infection in people that are not already infected,…

Hepatitis BChronic Hepatitis B

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT04843852

Phase 1

A Phase 1 Non-Randomized, Open-Label, Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function

This is a Phase 1 non-randomized, open-label, single-dose study of pevifoscorvir sodium (also known as ALG-000184) in participants with severe renal impairment…

Chronic Hepatitis B Infection

Estimated

~$10 – $8,750

Aligos TherapeuticsNCT07342881