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5 recruiting studies matching your filters

Sinus Disease in Young Children With Cystic Fibrosis

This is a prospective, observational study examining the impact of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators on ch…

Cystic Fibrosis in ChildrenCystic FibrosisChronic Rhinosinusitis (Diagnosis)+2 more

Estimated

~$10 – $750

University of California, Los AngelesNCT06191640

The Impact of Sinus Surgery in the Era of Highly Effective Modulatory Therapy

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS)…

Chronic Rhinosinusitis (Diagnosis)Cystic Fibrosis

Estimated

~$10 – $750

University of California, Los AngelesNCT04469439

Phase 2

Topical Probiotic Sinus Irrigations for the Treatment of Chronic Rhinosinusitis: a Double Blinded Randomized Controlled Trial

The purpose of this randomized study will be to determine whether topical probiotic sinus irrigations are more effective compared to saline sinus irrigation co…

Chronic Rhinosinusitis (Diagnosis)

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT05427695

Phase 1

The Role of IL5 in Epithelial Cell Integrity

The goal of this laboratory study is the examine the effect of mepolizumab drug on the health and function of the cells lining the human nasal airways in vitro…

Chronic Rhinosinusitis With Nasal PolypsChronic Rhinosinusitis (Diagnosis)

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT05895929

Phase 1

Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis (Randomized Pilot Study Utilizing Ivacaftor for the Treatment of Refractory Gram-Negative Bacterial CRS)

The purpose of this pilot study is to explore wither ivacaftor in refractory CRS patients will demonstrate safety and tolerability; restore CFTR-mediated Cl- s…

Chronic Rhinosinusitis (Diagnosis)

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT03439865