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21 recruiting studies matching your filters

A 12-Month, Open-Label Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Siplizumab as Induction Therapy in Patients With Autoimmune Liver Diseases Undergoing Liver Transplantation (SET-SAIL)

There is a significant unmet need for safe and effective therapeutic approaches to prevent immune-mediated graft injury and its complications in liver transpla…

Autoimmune Liver DiseaseLiver Transplant DisorderAutoimmune Hepatitis+3 more

Estimated

~$10 – $7,500

Elizabeth C. VernaNCT06455280

Phase 2

Phase II Randomized Controlled Trial of Epigallocatechin Gallate for Hepatocellular Carcinoma Chemoprevention

This phase II trial tests epigallocatechin gallate (EGCG) for its efficacy and safety in preventing development of hepatocellular carcinoma (HCC) in patients w…

Cirrhosis, Liver

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT06015022

Observational

Transitional Care Program vs Standard of Care in Cirrhosis With Volume Overload: A Pilot Study

The goal of this clinical trial is to learn about an intensive monitoring plan (transitional care program) in patients with cirrhosis and excessive swelling th…

Cirrhosis, Liver

Estimated

~$10 – $6,250

Milton S. Hershey Medical CenterNCT06174272

Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis

The goal of this research is to validate novel non-invasive Magnetic resonance imaging (MRI) biomarkers to detect Gastroesophageal varices (GEV) in patients wi…

Cirrhosis, LiverGastroesophageal VaricesFontan Procedure

Estimated

~$10 – $750

University of Wisconsin, MadisonNCT04867954

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver tra…

Cirrhosis, LiverDiabetes Mellitus RiskTransplant; Failure, Liver+1 more

Estimated

~$10 – $750

University of ChicagoNCT06950788

Phase 1

The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial

The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) trial is a single center prospective adaptive phase 1b clinical trial in patients who ar…

Liver DiseasesLiver FailureCirrhosis, Liver

Estimated

~$10 – $6,250

University of ChicagoNCT06871111

A Case Control Study in a Population With Clinical Suspicion of Liver Cirrhosis to Develop a Risk Model for the Presence of Cirrhosis Using Breath Biomarkers/EVOC Probes

Owlstone Medical has demonstrated that the use of an Exogenous Volatile Organic Compound (EVOC) that targets specific metabolic processes linked to cirrhosis p…

Cirrhosis, Liver

Estimated

~$10 – $1,050

Owlstone LtdNCT07035158

Observational

LiverPAL: A Randomized Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (A…

Liver Disease ChronicEnd Stage Liver DIseaseCirrhosis+2 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05998330

Phase 4

Comparison the Seroconversion Rate Between Two-dose and Three-dose Regimens of Heplisav B Among Patients With Cirrhosis, a Randomized-control Prospective Study.

Investigators want to compare the seroconversion rates between two-dose and three-dose regimens of the hepatitis B vaccine (Heplisav B) among patients with cir…

Hepatitis BCirrhosis, LiverChronic Liver Disease

Estimated

~$10 – $6,250

Mercy Medical CenterNCT04588077