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Phase 1
Allogeneic Stem Cell Transplantation Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion With Zoledronic Acid in Combination to Treat Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory Solid Tumors
Hematopoietic stem cell transplantation can cure patients with blood cancer and other underlying diseases. αβ-T cell and B cell depletion has been introduced t…
NeuroblastomaRhabdomyosarcomaSynovial Sarcoma+10 more
University of FloridaNCT06625190
Phase 1
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
3CAR is being done to investigate an immunotherapy for patients with solid tumors. It is a Phase I clinical trial evaluating the use of autologous T cells gene…
Pediatric Solid TumorOsteosarcomaRhabdomyosarcoma+13 more
St. Jude Children's Research HospitalNCT04897321
Phase 2
A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
This is a multi-center, open label, phase II study of tebentafusp in patients with unresectable or metastatic clear cell sarcoma (CCS).
HLA-A*0201 Positive Cells PresentClear Cell Sarcoma (CCS)
Sarcoma Alliance for Research through CollaborationNCT06942442