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Neuromodulation and Cognitive Behavioral Therapy for Insomnia in MCI
The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle…
Fall Prevention in Cognitively Impaired Older Veterans Through Neurophysiological Rehabilitation
Falls represent the leading cause of hospitalization, nursing home admissions, disability and mortality for older adults with annual healthcare costs over $50 …
Effects of Transcranial Ultrasound Stimulation (TUS) on Neurological and Cognitive Outcomes in Neurodegenerative Diseases.
The purpose of this study is to evaluate the safety and efficacy of transcranial focused ultrasound neuromodulation in improving neural function, cognitive and…
Cognitive Reserve and Linguistic Resilience in Bilingual Hispanics With Primary Progressive Aphasia
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates p…
Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
This clinical trial is focused on determining whether biological signatures of target engagement by a Centella asiatica water extract product administered oral…
Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy
The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such a…
CogMed Intervention Targeting Working Memory in Patients with Mild Cognitive Impairment
The purpose of this study is to test whether a special memory training program, called CogMed, can help people with early memory problems. The Investigators wa…
Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging)…
Latinas Integrating Fitness and Therapy (LIFT)
Investigators are studying how combining a stepped-care mental health counseling program with an evidence-based exercise program can help Latina cancer survivo…
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
Effective, clinically meaningful treatments are lacking for patients with mild cognitive impairment (MCI), which is associated with increased risk of transitio…
Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid, and Tau in Older Adults (IPAT Study)
The purpose of this study is to determine if intensive lowering of systolic blood pressure (SBP), using FDA approved medications (antihypertensive), reduces Al…
A Pragmatic Trial of the TabCAT Brain Health Assessment for the Detection of Cognitive Impairment in Primary Care
Efficient and user-friendly paradigms to detect cognitive impairment, including dementia are needed in primary care. The TabCAT Brain Health Assessment accurat…