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8 recruiting studies matching your filters

Evaluation of Provider vs. Patient Mediated Cascade Genetic Testing of First-Degree Relatives of Patients With Newly Diagnosed Colorectal Cancer

This clinical trial compares patient (proband)-mediated communication to provider-mediated communication for improving genetic testing in first-degree relative…

Colon AdenocarcinomaColorectal AdenocarcinomaRectal Adenocarcinoma+12 more

Estimated

~$10 – $6,250

Alliance for Clinical Trials in OncologyNCT07143487

Phase 3

A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 Versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)

Researchers are looking for other ways to treat locally advanced or metastatic colorectal cancer (mCRC) that is unresectable and has a gene mutation called KRA…

Colon AdenocarcinomaRectal Adenocarcinoma

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06997497

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

The purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-s…

Bladder CarcinomaUreter CarcinomaRenal Pelvis Carcinoma+14 more

Estimated

~$10 – $1,050

Guardant Health, Inc.NCT05059444

Phase 3

Evaluating Novel Therapies and ctDNA as a Marker in Curatively-Treated Gastrointestinal Cancers With Microscopic Residual Disease

This study is a non-randomized, open-label, multi-cohort, multi-site, pilot feasibility therapeutic trial. The study will enroll 20 patients across 4 cohorts (…

Colon AdenocarcinomaRectal AdenocarcinomaGastric Adenocarcinoma+4 more

Estimated

~$10 – $6,250

Georgetown UniversityNCT05482516

Phase 2

A Phase II Novel Exploratory Study to Test Neoadjuvant Immunotherapy Combinations in Patients With Resectable Colon Cancer (NEST3)

This phase II trial tests how well giving botensilimab and balstilimab prior or to surgery (neoadjuvent) works for the treatment of colorectal cancer that may …

Advanced Colon AdenocarcinomaAdvanced Colorectal AdenocarcinomaAdvanced Rectal Adenocarcinoma+10 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT07595874

Phase 1

Proof of Concept Study of ctDNA Guided Change in Treatment for Refractory Minimal Residual Disease in Colon Adenocarcinomas

This is a phase 1b, prospective, single arm, non-randomized, open-label clinical trial determining the efficacy of adjuvant trifluridine and tipiracil (TAS-102…

Colon AdenocarcinomaColorectal Cancer

Estimated

~$10 – $6,250

University of California, IrvineNCT04920032

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test (eAArly DETECT)

The Mainz Biomed Colorectal Cancer Screening Test is being studied for its performance in the identification of the presence of colorectal cancer (CRC) or adva…

Colorectal Cancer ScreeningColorectal Cancer MetastaticColon Adenocarcinoma

Estimated

~$10 – $1,125

Mainz BiomedNCT06864338

Phase 2

VIVA: Volatile or IV Anesthesia for Cancer

This trial evaluates how inhalational anesthesia (drawn in through the lungs) and total intravenous anesthesia (TIVA) (through a needle in a vein in the arm) c…

Colon Adenocarcinoma

Estimated

~$10 – $6,250

University of Kansas Medical CenterNCT06017141