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429 recruiting studies matching your filters

A Phase 1 Study to Evaluate the Safety and Efficacy of DISP-10 in Participants With Advanced Gastrointestinal Cancers

This is a Phase 1, multicenter, open-label study of DISP-10, a combination therapy consisting of DV-10 (adenovirus) and idecabtagene vicleucel (ide-cel, BCMA-d…

Colorectal CancerGastric AdenocarcinomaEsophageal Adenocarcinoma+1 more

Estimated

~$10 – $8,750

Dispatch BiotherapeuticsNCT07544589

Observational

Phase 1a/b Trial of Exercise as Interception Therapy for Primary High-Risk Cancer

Researchers think that exercise may be able to prevent cancer from coming back by lowering ctDNA levels. The purpose of this study is to explore how aerobic ex…

Breast CancerProstate CancerColorectal Cancer+9 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT04589468

Phase 2

Regorafenib (Reg) and Lorigerlimab (Lor), RELO Regimen, in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy [ReLOAD Trial]

To learn about the effects of the drugs regorafenib and lorigerlimab on circulating tumor DNA (ctDNA) in patients with CRC and who have radiographic occult min…

Colorectal CancerRegorafenibHigh Risk Patients

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT07071961

Observational

Expanding Access to Colorectal Cancer Screening Through Community Pharmacies: The PharmFIT Study

This study will conduct a randomized controlled trial to assess the impact of a pharmacy-based FIT intervention, Pharmacy-based FIT (PharmFIT), on colorectal c…

Colorectal Cancer

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT06656936

Metatranscriptomic Markers As A Predictor of Colonic Neoplasia at the Time of Colonoscopy

This study is a collaboration between Viome Life Sciences and Scripps Research Institute to develop and validate a noninvasive molecular diagnostic test for th…

Safety and Efficacy of Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Ovarian, Uterine, Appendiceal, Colorectal, and Gastric Cancer Patients With Peritoneal Carcinomatosis (PC)

This phase I trial studies the side effects of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in treating patients with ovarian, uterine, appendiceal…

Clinical Stage IV Gastric Cancer AJCC v8Clinical Stage IVA Gastric Cancer AJCC v8Clinical Stage IVB Gastric Cancer AJCC v8+24 more

Estimated

Phase 1

A Phase 1, First-in-human (FIH), Dose-Escalation and Dose-Optimization Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer

This study will investigate the safety, tolerability, pharmacokinetics, and anti-tumor activity of CBI-1214 in participants with advanced or metastatic Microsa…

Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more

Estimated

~$10 – $8,750

Cartography BiosciencesNCT07321106

Phase 2

Open-label Phase 2 Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

To investigate the efficacy of AMB-05X in patients with CRC with MRD as determined by a ctDNA(+) blood test and no clinically detectable radiographic disease.

Colorectal Cancer

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06617858

Phase 1

A Phase 1/2 Study of Tegavivint (NSC#826393) in Children, Adolescents, and Young Adults With Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come b…

Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more

Estimated

~$10 – $7,500

Phase 1

A Phase 1a/1b Trial of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

The main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherap…

Pancreatic Ductal AdenocarcinomaNon-small Cell Lung CancerColorectal Cancer

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT06586515

Observational

Improving Colorectal Cancer Screening Uptake Through Patient-Centered Education and Mailed Stool-Based Testing Outreach in the Primary Care Medicine Clinic

This is a mixed-methods implementation pilot combining an educational intervention with a mailed stool-based testing outreach feasibility study within a reside…

Colorectal Cancer (CRC) ScreeningCRC ScreeningRectal Cancer+2 more

Estimated

~$10 – $6,250

Washington University School of MedicineNCT07781774

Use of Viscoelastic Assays Beyond Coagulation: Pre- and Post-operative TEG

The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and…

Liver CancerEsophageal CancerColorectal Cancer+4 more

Estimated

~$10 – $750

University of Colorado, DenverNCT05517811