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23 recruiting studies matching your filters

Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Right and Left Congenital Diaphragmatic Hernia (CDH)

The purpose of this research study is to see if the FETO surgery and FETO release (surgery to remove the device) works and is safe for babies with severe right…

Congenital Diaphragmatic Hernia

Estimated

~$10 – $6,250

University of Colorado, DenverNCT03674372

Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science

The goal of this study is to identify genes that convey susceptibility to congenital diaphragmatic hernia in humans. The identification of such genes, and exam…

Congenital Diaphragmatic Hernia

Estimated

~$10 – $750

Columbia UniversityNCT00950118

Phase 2

A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)

Congenital diaphragmatic hernia (CDH) occurs in approximately 1 in 3000 US live births, similar to the incidence seen within the Utah Birth Defects cohort. The…

Congenital Diaphragmatic HerniaPulmonary Hypertension

Estimated

~$10 – $6,250

University of UtahNCT05201144

Phase 3

Safety and Efficacy of FETO in CDH Phase III

Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses and standard of care control group

Congenital Diaphragmatic HerniaPulmonary HypoplasiaPulmonary Hypertension

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT07187206

Observational

A Study of the Effectiveness of Fetal Endoscopic Tracheal Occlusion (FETO) in the Management of Severe Prenatally Diagnosed Congenital Diaphragmatic Hernia (CDH)

The purpose of the study is to study the efficacy of fetal endoscopic tracheal occlusion (FETO) in cases of severe congenital diaphragmatic hernia (CDH). This …

Congenital Diaphragmatic Hernia

Estimated

~$10 – $7,500

Yair BlumenfeldNCT05461222

Observational

Fetal Endoscopic Tracheal Occlusion Trial for Congenital Diaphragmatic Hernia (CDH)

This is a single site pilot trial to assess the feasibility and safety of treating severe CDH with Fetal Endoscopic Tracheal Occlusion with the Goldballoon Det…

Congenital Diaphragmatic Hernia

Estimated

~$10 – $7,500

Dr Erin PerroneNCT04052828

Observational

Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia

Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses.

Congenital Diaphragmatic HerniaPulmonary HypoplasiaPulmonary; Hypertension

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT02986087

Observational

A Prospective Study on the Role of Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension Among Fetuses With Severe Congenital Diaphragmatic Hernia

Congenital diaphragmatic hernia (CDH) occurs when the diaphragm fails to fully fuse and leaves a portal through which abdominal structures can migrate into the…

Congenital Diaphragmatic Hernia

Estimated

~$10 – $7,500

Michael A BelfortNCT03980717

Observational

Fetal Endoscopic Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH) NCT3138863

The purpose of this research is to gather information on the safety and effectiveness of a new procedure called Fetoscopic Endoluminal Tracheal Occlusion (FETO…

Congenital Diaphragmatic HerniaPulmonary HypoplasiaPulmonary Artery Hypertension

Estimated

~$10 – $7,500

Rodrigo RuanoNCT03138863

Observational

Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia (CDH)

This is a single site pilot trial to study the feasibility of Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in the most severe group of fetuses with…

Congenital Diaphragmatic Hernia

Estimated

~$10 – $7,500

Aimen F. Shaaban, MDNCT05450653

Observational

North American Fetal Therapy Network Prospective Registry for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia

This registry study aims to confirm that FETO increases neonatal survival to discharge and reduces long-term morbidity in fetuses with isolated left CDH and o/…

Congenital Diaphragmatic HerniaCongenital AbnormalitiesNeonatal Diseases and Abnormalities+5 more

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT07166172