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5 recruiting studies matching your filters

A Phase 1/2 Study of FOG-001 in Participants With Locally Advanced or Metastatic Solid Tumors

The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in partici…

CancerColorectal CancerSolid Tumor+12 more

Estimated

~$10 – $8,750

Parabilis Medicines, Inc.NCT05919264

Phase 2

Tovorafenib for the Treatment of Newly Diagnosed or Recurrent Craniopharyngioma in Children and Young Adults

The current study assesses the tolerability and efficacy of monotherapy with pan-RAF-kinase (Tovorafenib) inhibition for the treatment of children and young ad…

Craniopharyngioma, ChildCraniopharyngiomaRecurrent Craniopharyngioma

Estimated

~$10 – $7,500

Sabine Mueller, MD, PhDNCT05465174

Phase 2

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA® (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma

ACTEMRA (tocilizumab) is an IL-6 receptor antagonist used for the treatment of adult Rheumatoid Arthritis as well as Polyarticular (PJIA) and Systemic (SJIA) J…

Adamantinomatous CraniopharyngiomaRecurrent Adamantinomatous Craniopharyngioma

Estimated

~$10 – $6,250

Nationwide Children's HospitalNCT05233397

Phase 2

Phentermine/Topiramate in Children, Adolescents, and Young Adults With Hypothalamic Obesity: a Pilot and Feasibility Study

Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant for…

Hypothalamic ObesityHypothalamic TumorCraniopharyngioma

Estimated

~$10 – $6,250

Seattle Children's HospitalNCT06299891

Phase 2

Phase 2 Study of the MEK Inhibitor MEKTOVI® (Binimetinib) for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

MEKTOVI (binimetinib) is an oral, highly selective reversible inhibitor of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2. The biolo…

Adamantinous CraniopharyngiomaRecurrent Adamantinomatous Craniopharyngioma

Estimated

~$10 – $6,250

Nationwide Children's HospitalNCT05286788