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8 recruiting studies matching your filters

A Phase 3 Randomized Study of Intralesional Cemiplimab Versus Primary Surgery in Participants With Early Stage Cutaneous Squamous Cell Carcinoma (CSCC)

This study will test a study drug called cemiplimab to see if it can help treat early-stage Cutaneous Squamous Cell Carcinoma (CSCC), a type of skin cancer. Ce…

Cutaneous Squamous Cell Carcinoma (CSCC)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT06585410

Phase 2

A Phase 2 Study of Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma (CONTRAC-2)

This is a phase II, multicenter, open label, single arm, non-randomized trial using Simon's optimal two-stage design to evaluate the efficacy of cemiplimab in …

Kidney Transplant RecipientCutaneous Squamous Cell Carcinoma (CSCC)Advanced Cutaneous Squamous Cell Carcinoma+1 more

Estimated

~$10 – $6,250

Washington University School of MedicineNCT07715734

Phase 1

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Organ Transplant Recipients This study is designed to evaluate whether a…

Skin CancerCutaneous Squamous Cell Carcinoma (CSCC)Actinic Keratosis (AK)+1 more

Estimated

~$10 – $7,500

Marissa LoblNCT07286318

Phase 2

MOHs Surgery and Adjuvant Short-course Hypofractionated Radiation Therapy With Structured Surveillance for Cutaneous Head & Neck Squamous Cell Carcinoma: a Phase II Pilot Study (MOHSAHRTSS-Study)

The goal of this clinical trial is to evaluate if short-course radiation therapy (SCRT) can effectively treat high-risk cutaneous squamous cell carcinoma (cSCC…

Cutaneous Squamous Cell Carcinoma (CSCC)

Estimated

~$10 – $6,250

University of Vermont Medical CenterNCT06998342

Phase 1

A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision

This study is investigating the effects on immune cells of injecting the influenza vaccine (also known as "flu shot") into cutaneous squamous cell carcinoma (C…

Skin CancerCutaneous Squamous Cell Carcinoma (CSCC)Cutaneous Squamous Cell Cancer

Estimated

~$10 – $7,500

Dana-Farber Cancer InstituteNCT06664151

Phase 2

Phase 2 Pragmatic Trial Investigating Sentinel Lymph Node Biopsy (SLNB) Efficacy and Safety in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

This is a phase 2 pragmatic study at a single site that evaluates the clinical benefit of SLNB in patients with high-risk cSCC and cN0. The primary goal is to …

Cutaneous Squamous Cell Carcinoma of the Head and NeckClinically Node-Negative (cN0)High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

Estimated

~$10 – $6,250

University of California, DavisNCT06990737

Tumor-informed ctDNA Testing for Minimal Residual Disease Monitoring Following Curative-intent Treatment of Squamous Cell Carcinoma of the Head and Neck.

This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for …

Squamous Cell Carcinoma of Head and NeckSquamous Cell Carcinoma Head and Neck Cancer (HNSCC)Squamous Cell Carcinoma of Skin+1 more

Estimated

~$10 – $675

University of California, San FranciscoNCT06606028

Phase 1

A Phase 1/1b Study of VET3-TGI Administered Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors

VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study is designed…

Solid Tumor, AdultMicrosatellite Stable Colorectal CancerHead and Neck Squamous Cell Carcinoma+10 more

Estimated

~$10 – $8,750

KaliVir ImmunotherapeuticsNCT06444815