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149 recruiting studies matching your filters

NOX4, Mitochondria and Related Biomarkers in Autosomal Dominant Polycystic Kidney Disease

To determine the value of NOX4, markers of mitochondria injury and function, and oxidative stress as real-time biomarkers to assess disease severity in patient…

Autosomal Dominant Polycystic Kidney Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT04630613

Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)

The prevalence of childhood obesity in the United States has more than tripled in the past four decades affecting one in every five adolescent girls and is dis…

Polycystic Ovarian Syndrome in Adolescent FemalesObesity (Disorder)

Estimated

~$10 – $750

Actual pay is set by the research site.

Nemours Children's ClinicNCT07169136

Remote Sputum Collection in Adults With Cystic Fibrosis

Elexacaftor/Tezacaftor/Ivacaftor or Trikafta improves lung health in people with cystic fibrosis (CF), including decreased cough and mucous production. Diagnos…

Cystic FibrosisInfections

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT06950892

Natural History of Treated Neurocysticercosis and Long-Term Outcomes

Neurocysticercosis is a brain disease due to the larval stage of the pork tapeworm (Taenia solium). The most common symptoms patient experience from infection …

CysticercosisNeurocysticercosis

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001205

Phase 2

A Phase 2, Multicenter, Randomized, Active-controlled Study to Assess the Safety and Efficacy of ANG003 at Two Different Dose Levels in Subjects With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

In this study, ANG003, a pancreatic enzyme replacement therapy (PERT; commonly called "enzymes"), is being investigated as a potential treatment for exocrine p…

Exocrine Pancreatic Insufficiency (EPI)Cystic Fibrosis (CF)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Anagram Therapeutics, Inc.NCT07450547

Phase 4

A Multicenter Trial of Iron Repletion in Cystic Fibrosis: IRON-CF

The researchers in this study hope to learn whether oral (PO) or intravenous (IV) iron treatments are better for treating iron deficiency in patients with cyst…

Cystic FibrosisIron DeficienciesIron Deficiency Diseases

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of MichiganNCT07903311

Phase 1

A Phase 1, Open-Label, Mass Balance Study to Investigate the Absorption, Distribution, Metabolism, and Excretion of 14C-VX-407 Following Single Oral Administration in Healthy Subjects

The purpose of the study is to evaluate the pharmacokinetics, safety and tolerability of VX-407 following a single oral dose.

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Vertex Pharmaceuticals IncorporatedNCT07868926

Natural History of Bronchiectasis

Bronchiectasis is a chronic inflammatory and muco-obstructive condition that results in abnormal dilation of the airways, decline in lung function, frequent ex…

BronchiectasisCystic FibrosisAutoimmune Disease+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT00943514

Natural History of Noncirrhotic Portal Hypertension

Background: \- Noncirrhotic Portal Hypertension (NCPH) is caused by liver diseases that increase pressure in the blood vessels of the liver. It seems to start…

Cystic FibrosisImmunologic Deficiency SyndromeTurner Syndrome+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT02417740

DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

Background: \- Pleuropulmonary blastoma (PPB) is a rare fast-growing lung tumor that is associated with other, rare tumor types. Most cases of PPB appear in c…

Pleuropulmonary BlastomaCystic NephromaOvarian Sertoli-Leydig Cell Tumors+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT01247597

Phase 1

Phase I/II Trial of Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

Background: Head and neck cancers (HNCs) account for about 5% of all cancers worldwide. They grow in the mouth, throat, nasal cavity, or salivary glands. Pros…

Head and Neck CancerHead and Neck Squamous Cell CarcinomaParanasal Sinus Neoplasms+9 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)

Phase 2

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis (ATMOS)

The purpose of the study is to investigate the efficacy of galvokimig versus placebo on the time to the first pulmonary exacerbation in study participants with…

Non-cystic Fibrosis Bronchiectasis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

UCB Biopharma SRLNCT07720375