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149 recruiting studies matching your filters

Exploring Caregiver Needs While Supporting People with CF Learning About Lung Transplant

Lung transplant is an option for treating end-stage lung disease in cystic fibrosis (CF). In the United States, more people with CF and low lung function die e…

Cystic Fibrosis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of WashingtonNCT06032273

Phase 1

A Phase 1/2, Multicenter, Open-label Study of REM-422, a MYB mRNA Degrader, in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with advanced Adenoid Cystic Carcinoma (ACC)

Adenoid Cystic CarcinomaMetastatic Adenoid Cystic CarcinomaRecurrent Adenoid Cystic Carcinoma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Remix TherapeuticsNCT06118086

Prospective Analysis of Urine LAM to Eliminate NTM Sputum Screening (PAINLESS Trial)

This is a prospective, single-center, nonrandomized observational study to investigate the utility of urine lipoarabinomannan (LAM) as a test to identify indiv…

Cystic Fibrosis

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Jerry A. Nick, M.D.NCT04579211

Phase 3

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

Girls and women 12-35 years old with obesity and polycystic ovarian syndrome who are on or off metformin, will receive a glucagon like peptide-1 receptor agoni…

PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesObese

Estimated

~$50 – $1,500

Actual pay is set by the research site.

University of Colorado, DenverNCT05819853

Observational

Revamping Exercise Assessments in Child Health (Project REACH)

This study is a cooperative investigation funded by the NIH. The project is a collaboration among three major NIH Clinical Translational Science Awardees: 1) U…

Cystic FibrosisSickle Cell DiseaseSARS CoV 2 Infection

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, IrvineNCT05359991

Phase 2

The Effect of Verapamil on Beta Cell Function in Adolescents and Adults With Cystic Fibrosis-related Dysglycemia

The investigators are conducting a pilot open-label pre/post interventional trial in adolescents and adults with cystic fibrosis (CF) and abnormal glucose tole…

Cystic Fibrosis Related DiabetesCystic Fibrosis (CF)Abnormal Glucose Tolerance

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Rhode Island HospitalNCT07688070

Phase 2

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of ABBV-CLS-628 in Adult Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that causes fluid-filled cysts to develop in the kidney…

Autosomal Dominant Polycystic Kidney Disease

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Calico Life Sciences LLCNCT06902558

Observational

A Prospective Series of IVF Cases Utilizing in Vitro Maturation (IVM) With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Embryo Transfer Using a Subsequent Frozen Embryo Transfer Cycle

A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols i…

Polycystic Ovary Syndrome

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Bruce Rose, MDNCT04149496

Phase 2

Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I)

Phase II open label study designed to evaluate the efficacy and safety of P-Sam in patients with aggressive, solid, NOTCH mutant or p63 low (B7-H4 high) R/M AC…

Adenoid Cystic Carcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT07162480

Observational

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

Developed nations worldwide are currently enduring a health crisis, as chronic diseases continue to decrease quality of life and promote additional disease sta…

ObesityHyperlipidemiasPolycystic Ovary Syndrome+6 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

West Virginia School of Osteopathic MedicineNCT06049420

Phase 2

Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults With Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a Randomized, Open-label, Cross-over Trial

Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced β-cell mass contributes t…

Cystic FibrosisPancreatic InsufficiencyAbnormal Glucose Tolerance+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of PennsylvaniaNCT04731272

Phase 1

A Phase 1 Dose Escalation and Expansion Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 in Subjects With Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

This open-label clinical trial will evaluate the safety and tolerability of NN3201 in subjects with advanced and/or metastatic solid tumors known to express c-…

Gastrointestinal Stromal TumorsSmall-cell Lung CancerAdenoid Cystic Carcinoma+4 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Novelty Nobility, Inc.NCT06805825