This study will evaluate BCB-276, an investigational B7-H3-targeted Chimeric Antigen Receptor (CAR) T cell therapy, in children and young adults with diffuse i…

Diffuse Intrinsic Pontine GliomaDIPGBrain Tumor+9 more

~Estimated

~$10 – $8,750

BrainChild Bio, IncNCT07680439

Phase 1

Open Label Phase 1 and Target Validation Study of ONC206 in Children and Young Adults With Newly Diagnosed or Recurrent Diffuse Midline Glioma (DMG), and Other Recurrent Primary Malignant Central Nervous System (CNS) Tumors

This phase I trial studies the effects and best dose of ONC206 alone or in combination with radiation therapy in treating patients with diffuse midline gliomas…

Diffuse Midline Glioma (DMG)GlioblastomaRecurrent Ependymoma+5 more

~Estimated

~$10 – $7,500

Sabine Mueller, MD, PhDNCT04732065

A Retrospective and Prospective Observational Sub-Study for Diffuse Midline Glioma and Diffuse Intrinsic Pontine Glioma

This study will gather data from new and existing patients with patient medical records, and patient/family/caregiver reported information to establish a clear…