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Assessing the Safety, Tolerability, and Efficacy of Psilocybin Therapy Followed by Accelerated Intermittent Theta Burst (aiTBS) Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment-Resistant Major Depressive Disorder
The purpose of this study is to determine the safety and feasibility of sequencing psilocybin therapy with a short-duration, aiTBS protocol (Stanford Accelerat…
The Mental Health Experiences of Hispanic and Latinx Dementia Caregivers
The goal of this observational study is to understand how contextual, individual-level, and cultural factors influence the daily and long-term well-being of ca…
Digital InteGrated Behavioral TreatmeNt for Comorbid ObesITy and DeprEssion Among Racial and Ethnic Adults Age 50 and Older (IGNITE)
The goal of this randomized clinical trial is to test the efficacy of a fully digital intervention, combining the Lumen problem-solving therapy virtual coach f…
The Oh Happy Day Class - Digital Connections (OHDC-DC): an Exploratory Pilot Study
The goal of this clinical trial is to see if a mobile phone app can deliver depression treatment to African Americans who are depressed. The main question it a…
Establishing Multimodal Brain Biomarkers Using Data-driven Analytics for Treatment Selection in Depression
The purpose of the study is to identify brain biomarkers and characteristics that predict individual responses to treatment of major depression with the antide…
Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story
The main goal of this research is to help families who are experiencing food insecurity (FI) and help mothers with depression. The next goal is to provide oth…
PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)
Background: Researchers developed \[11C\]MC1, a radioligand for cyclooxygenase-2 (COX-2). COX-2 is an enzyme induced in the brain during inflammation. Researc…
Multidimensional Sleep Health Intervention to Optimize Concussion Recovery: A Randomized Clinical Trial
Following adolescent concussion, poor sleep health is common and relates to the development of persisting post-concussion symptoms, and uninjured adolescents (…
Harlem Strong Mental Health Coalition: A Multi-sector Community-Engaged Collaborative for System Transformation
Addressing health disparities, especially in the face of coronavirus pandemic, requires an integrated multi-sector equity-focused, community-based approach. Th…
Resilience in Adolescent Development
RAD is a 10-year natural history, longitudinal, prospective assessment study of a cohort of 2,500 participants (ages 10-24 years) that will help uncover the so…
Virtual Reality Training Study
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Trainin…
Group-based Prevention of Postpartum Depression: In-person vs. Virtual Delivery
The goal of this clinical trial is to test whether an established preventive intervention (group interpersonal therapy) delivered virtually shows the same bene…