Find your next paid study

University of MichiganNCT06721559

DepressionECTCognitive Change

Amplitude Titration to Improve ECT Clinical Outcomes Randomized Clinical Trial

A randomized controlled trial will compare hippocampal neuroplasticity, antidepressant, and cognitive outcomes between individualized amplitude and fixed 800 m…

University of New MexicoNCT05699226

Phase 1

Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder

The goal of this clinical trial is to learn if a single dose of psilocybin (5mg Vs 10mg Vs 25mg) alongside psychotherapy is safe and can help treat treatment r…

Treatment Resistant DepressionSubstance Use Disorders

Indiana UniversityNCT07499583

Phase 2

A Double-blind, Placebo-controlled, Phase IIA Human Laboratory Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

This study will evaluate the safety and exploratory efficacy of AFA-281 in patients with Alcohol use disorder on cravings, subjective response to alcohol, pain…

Alcohol AbuseAlcohol Abuse/addictionAnxiety+3 more

DepressionSelective Serotonin Reuptake Inhibitor

~$10 – $8,750

Afasci IncNCT06710431

Thermoregulatory Responses to Heat Stress in Adults With Major Depressive Disorder With and Without Antidepressant Treatment

The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat str…

Penn State UniversityNCT06805851

~$10 – $750

Phase 3

An Open-Label Pilot Study of Creatine for Depressed Male and Female Methamphetamine Users

* Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users * Assess creatine's effect on methamphetamine use * Assess t…

DepressionAnxietyMethamphetamine Dependence

Montana State UniversityNCT02568878

Phase 1

Mood Effects of Serotonin Agonists: Depression

This study will examine the effect of a low dose of the 5HT2A agonist LSD (26 µg), compared to placebo, on acute and protracted mood states in individuals with…

LSDMajor Depressive DisorderDepression

University of ChicagoNCT07017478

Phase 4

Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by double-blind, randomized adjunctive treatment with clonazepam…

Anxious DepressionDepression

University of CincinnatiNCT04245748

~$10 – $5,625

PTSD - Post Traumatic Stress DisorderPTSD and Alcohol Use DisorderPTSD and Trauma-related Symptoms+8 more

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people …

University of ArkansasNCT06923423

StressDepressionPregnancy+1 more

Efficacy of a Culturally-sensitive Telehealth Platform in Fostering Community-based Care Coordination for Respectful Maternal Care

The Cocooned Moms Study is a pre- and post-design study primarily aimed at reducing stress, depressive symptoms, and blood pressure among expectant Black women…

InovCares Connected Comprehensive Healthcare CorporationNCT06968650

~$10 – $8,750

PTSDDepressionChild Maltreatment

Treating Maternal PTSD to Enhance and Reduce Maltreatment Recidivism: Safe Mothers, Safe Children

The purpose of this study is to assess the efficacy of the combined interventions, Skills Training in Affective and Interpersonal Regulation (STAIR) and Parent…

New York UniversityNCT04752618

DepressionParent-Child Relations

Maternal Positive Affect Socialization and Child Neural Reward Response

The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response…