Dermatomyositis (DM) is a rare autoimmune disease that causes muscle weakness, skin rashes, and other symptoms. Researchers think both genetic and environmenta…

Dermatomyositis (DM)Juvenile Dermatomyositis (JDM)

~Estimated

~$10 – $5,625

National Institute of Environmental Health Sciences (NIEHS)NCT07111065

Phase 1

A Phase 1 Study of Allogeneic (γ/δ) BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease

Therapy with chimeric antigen receptor T (CAR-T) cells has demonstrated activity against refractory autoimmune disease, however not all disease responds or rem…

Rheumatoid Arthritis (RA)Systemic Lupus Erthematosus (SLE)Dermatomyositis (DM)+1 more

~Estimated

~$10 – $8,750

Luminary TherapeuticsNCT07729995

Phase 1

Phase 1b Open-label Basket Trial of RAY121 to Inhibit Classical Complement Pathway in Immunological Diseases (RAINBOW Trial)

This Phase 1b basket trial will investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity and preliminary efficacy of RAY121, a …

Antiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more

~Estimated

~$10 – $8,750

Chugai PharmaceuticalNCT06371417