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7 recruiting studies matching your filters

A Phase 1/2 Study of DS-8201a (NSC# 807708) in Children, Adolescents, or Young Adults With Recurrent Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

This phase I/II trial studies the effects of trastuzumab deruxtecan (DS-8201a) in treating patients with osteosarcoma, Wilms tumor (WT) or desmoplastic small r…

Desmoplastic Small Round Cell TumorOsteosarcomaRecurrent Desmoplastic Small Round Cell Tumor+5 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04616560

Phase 1

Precision Analysis of Fusion Genes in Ewing Sarcoma (ES) and Desmoplastic Small Round Cell Tumor (DSRCT), Then EWSR1 Immunotherapy Without or With Anti-PD1 (Pembrolizumab)

This study is for people who have high-risk Ewing sarcoma (ES), or a related Ewing's family tumor, desmoplastic small round cell tumor (DSRCT). The purpose of …

Ewing SarcomaDesmoplastic Small Round Cell Tumor

Estimated

~$10 – $7,500

Rabi HannaNCT07695311

Phase 1

Lurbinectedin in FET-Fusion Tumors (LIFFT)

The purpose of this study is to find out if a drug called lurbinectedin (the "study drug") is safe and effective at treating people with recurrent or relapsed …

Ewing SarcomaDesmoplastic Small Round Cell TumorPediatric Cancer+1 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT05918640

Phase 1

Allogeneic Stem Cell Transplantation Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion With Zoledronic Acid in Combination to Treat Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory Solid Tumors

Hematopoietic stem cell transplantation can cure patients with blood cancer and other underlying diseases. αβ-T cell and B cell depletion has been introduced t…

NeuroblastomaRhabdomyosarcomaSynovial Sarcoma+11 more

Estimated

~$10 – $6,250

University of FloridaNCT06625190

Phase 1

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

3CAR is being done to investigate an immunotherapy for patients with solid tumors. It is a Phase I clinical trial evaluating the use of autologous T cells gene…

Pediatric Solid TumorOsteosarcomaRhabdomyosarcoma+13 more

Estimated

~$10 – $6,250

St. Jude Children's Research HospitalNCT04897321

Registry for Patients With Desmoplastic Small Round Cell Tumor

This study is a patient registry of people with Desmoplastic Small Round Cell Tumor (DSRCT). A patient registry is a collection of health information about a g…

Desmoplastic Small Round Cell Tumor

Estimated

~$10 – $750

Memorial Sloan Kettering Cancer CenterNCT04690374

Phase 1

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

This research is being done to test a new drug called PEEL-224 in combination with two commercially available drugs, Vincristine and Temozolomide, and to deter…

SarcomaSarcoma, EwingDesmoplastic Small Round Cell Tumor+3 more

Estimated

~$10 – $7,500

David S Shulman, MDNCT06709495