This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous syst…

Basal Ganglia GerminomaDiabetes InsipidusGerminoma+3 more

~Estimated

~$10 – $7,500

Children's Oncology GroupNCT06368817

Phase 1

A Phase 1b, Open-label Trial to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of NDI-5001 in a Capsule Following Daily Oral Doses to Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus

The primary purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of NDI-5001 administered as a capsu…

Diabetes Insipidus

~Estimated

~$10 – $8,750

Otsuka Pharmaceutical Development & Commercialization, Inc.NCT07525960

Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study

In this study, the investigators hypothesize that studying monogenic variants with strong effect associated with severe insulin deficiency of Wolfram syndrome …

Wolfram SyndromeDiabetes MellitusOptic Nerve Atrophy+3 more

~Estimated

~$10 – $750

Washington University School of MedicineNCT02841553