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Phase 2
A Phase II Trial Evaluating Chemotherapy Followed by Response-Based Reduced Radiation Therapy for Patients With Central Nervous System Germinomas
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous syst…
Basal Ganglia GerminomaDiabetes InsipidusGerminoma+3 more
Children's Oncology GroupNCT06368817
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study
In this study, the investigators hypothesize that studying monogenic variants with strong effect associated with severe insulin deficiency of Wolfram syndrome …
Wolfram SyndromeDiabetes MellitusOptic Nerve Atrophy+3 more
Washington University School of MedicineNCT02841553