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Phase 1
A Phase I/IIa, Single Site, Open-Label, Ascending Dose Study to Evaluate the Safety and Efficacy of OPF-310 [Encapsulated Porcine Islet Cells for Xenotransplantation] in Subjects With Type 1 Diabetes Mellitus
This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tole…
Diabetes Mellitus, Type 1HypoglycemiaIslet Cell Transplantation+14 more
Otsuka Pharmaceutical Factory, Inc.NCT06575426
Phase 1
CBTi for the Treatment of Insomnia in Type 1 Diabetes
The goal of this study is to learn if treating insomnia with a therapy intervention in people with type 1 diabetes will help to better control sugar levels, sl…
Diabetes Mellitus Type 1Insomnia
University of Illinois at ChicagoNCT07091318
Phase 3
Effectiveness and Safety of Sotagliflozin in Slowing Kidney Function Decline in Persons With Type 1 Diabetes and Moderate to Severe Diabetic Kidney Disease
Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available…
Diabetic NephropathiesKidney Failure, ChronicDiabetes Mellitus Type 1+1 more
Alessandro DoriaNCT06217302