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Phase 2
Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediat…
Diabetes Mellitus, Type 1Diabetes type1Autoimmune Diabetes
Massachusetts General HospitalNCT05180591
Phase 2
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect in new on…
Diabetes MellitusType 1 DiabetesDiabetes type1+1 more
Massachusetts General HospitalNCT05866536
Phase 2
Obesity Complicating Type 1 Diabetes in Young Adults: Physiology and Impact of GLP-1 Analogue Anti-obesity Treatment on Cardiometabolic Risk Factors
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular e…
Diabetes type1Obesity
Yale UniversityNCT06411210
Observational
Fusing Rapid-cycle Testing and Adaptive Trial Designs: A Scientific Pipeline to Translate and Individualize Evidence-based Psychosocial and Behavioral Interventions in Routine Type 1 Diabetes Care
This study is designed to compare two behavioral approaches to reduce diabetes distress ("the expected burdens, concerns, fears, and threats that arise from th…
Diabetes type1Diabetes Mellitus, Type 1Diabetes, Autoimmune+2 more
University of North Carolina, Chapel HillNCT06405373