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91 recruiting studies matching your filters

Sinus Disease in Young Children With Cystic Fibrosis

This is a prospective, observational study examining the impact of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators on ch…

Cystic Fibrosis in ChildrenCystic FibrosisChronic Rhinosinusitis (Diagnosis)+2 more

Estimated

~$10 – $750

University of California, Los AngelesNCT06191640

The Impact of Sinus Surgery in the Era of Highly Effective Modulatory Therapy

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS)…

Chronic Rhinosinusitis (Diagnosis)Cystic Fibrosis

Estimated

~$10 – $750

University of California, Los AngelesNCT04469439

Observational

Refining a Mind-Body Sexual Well-Being Program for Female GI Cancer Survivors

This record describes two distinct study phases: 1) A small open pilot trial including up to 10 participants, intended to generate descriptive feedback on rega…

Colorectal Cancer (Diagnosis)Anal CancerSexual Dysfunction Female

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07795801

Phase 1

Supplementary Neuromuscular Rehabilitation During Acute Concussion Recovery

Approximately 1.6 to 3.8 million mild traumatic brain injuries, or concussions, occur yearly in the United States. Although most individuals progress through r…

Concussion (Diagnosis)Gait Abnormality

Estimated

~$10 – $6,250

Northern Illinois UniversityNCT07801482

Phase 2

HIT HEADS 3.0: Head Injury Treatment: A Randomized, Placebo-controlled, Double-blinded, Therapeutic Clinical Trial of Branched Chain Amino Acids (BCAAs) in the Treatment of Concussion

This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAAs) in the treatment o…

Concussion (Diagnosis)MTBI - Mild Traumatic Brain InjuryConcussion, Brain+1 more

Estimated

~$10 – $7,500

Akiva CohenNCT07670195

Phase 1

Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) Recipients With Hematologic Malignancies (HM)

This is a first in children prospective study of allogeneic hematopoietic cell transplant using a centrally manufactured engineered donor graft (Orca-Q). The s…

Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMixed Phenotype Acute Leukemia+4 more

Estimated

~$10 – $6,250

University of FloridaNCT05322850

Phase 2

Phase II Basket Trial of Intraperitoneal Paclitaxel Plus Systemic Therapy in Gastrointestinal Malignancies With Peritoneal Carcinomatosis (STOPGAP - B)

This is a phase II open-label, basket clinical trial to assess the feasibility of systemic and Intraperitoneal chemotherapy in subjects with Gastrointestinal M…

Esophageal CarcinomaGastric Cancer (Diagnosis)Colorectal Adenocarcinoma+3 more

Estimated

~$10 – $6,250

University of California, IrvineNCT07795749

Phase 1

Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617 in a Prostatectomy Model (LUTACT Trial)

There is evidence that Actinium-225 Prostate-Specific Membrane Antigen (225Ac-PSMA) has a potentially higher level of efficacy than 177 Lutetium Prostate-Speci…

Prostate CancerProstate Cancer (Diagnosis)High-risk Prostate Cancer+2 more

Estimated

~$10 – $7,500

Thomas HopeNCT07054346

Observational

A Phase IIb, Randomized, Double-Blinded, Three-Arm Clinical Trial: The Study of Liposomal Bupivacaine Via Intercostal Nerve Block, Serratus Anterior Plane Block, or Combination Block for Pain Control After Robotic Thoracic Surgery

The goal of this clinical trial is to assess how the location of local anesthetic medication affects pain control capabilities in adult patients undergoing tho…

Lung Cancer (Diagnosis)

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07254650

A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground Truth

This prospective observational study will enroll men referred for prostate biopsy due to elevated PSA and/or abnormal digital rectal examination, with or witho…

Prostate CancerUrologyProstate Cancer (Diagnosis)

Estimated

~$10 – $1,050

Wren Laboratories LLCNCT07454603

Phase 4

Methenamine Hippurate Compared to Typical Antibiotic Prophylaxis in the Prevention of Urinary Tract Infection Following Intradetrusor OnabotulinumtoxinA Injection for Treatment of Overactive Bladder: a Randomized Controlled Non-Inferiority Trial

The goal of this clinical trial is to compare methenamine hippurate prophylaxis to routine antibiotic prophylaxis following onabotulinumtoxinA (BOTOX-A) inject…

Overactive Bladder (OAB)Urinary Tract Infection (Diagnosis)

Estimated

~$10 – $6,250

Women and Infants Hospital of Rhode IslandNCT06953271

Phase 2

Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): A Phase 2 Prospective Randomized Open Blinded End-point (PROBE) Design, Randomized Clinical Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma

Acute asthma exacerbation is caused by dysregulated pulmonary inflammatory pathways such that standard treatment includes prompt administration of exogenous sy…

Asthma (Diagnosis)

Estimated

~$10 – $6,250

Johns Hopkins All Children's HospitalNCT07455396