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Selpercatinib to Enhance RAI Avidity in Children, Adolescents, and Young Adults With Newly Diagnosed Differentiated Thyroid Cancers Harboring RET Fusions

Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced …

Differentiated Thyroid CancerPediatric CancerCancer+1 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT06458036

Targeted Therapy to Increase RAI Uptake in Patients With Metastatic Differentiated Thyroid Cancer

Papillary thyroid cancer (PTC) is a common type of differentiated thyroid cancer (DTC) in children and represents the second most common cancer in adolescent f…

Papillary Thyroid CancerPediatric CancerDifferentiated Thyroid Cancer

Estimated

~$10 – $750

Children's Hospital of PhiladelphiaNCT05024929

Phase 2

Larotrectinib to Enhance RAI Avidity in Patients With Differentiated Thyroid Cancer Harboring NTRK Fusions (LANTERN)

Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced …

Differentiated Thyroid CancerPediatric CancerCancer+1 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT05783323

Observational

Efficacy of a Patient-facing Decision Aid in Reducing Decision Anxiety and Improving Decision Readiness in Low Risk Thyroid Cancer

Low-risk thyroid cancer grows very slowly. More than 99% of patients with this cancer survive for at least 5 years. There are 3 main treatment options: remove …

Differentiated Thyroid Cancer (DTC)Papillary Thyroid MicrocarcinomaPapillary Thyroid Carcinoma

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT07536412