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Phase 1
Evaluation of 18F-Fluciclovine PET-MRI to Differentiate Tumor Progression From Post-treatment Changes in Pediatric High-grade Glioma (HGG)
The purpose of this study is to see if 18F-fluciclovine (Axumin®) PET imaging is useful and safe in the management of children with High Grade Gliomas. Investi…
GliomaHigh Grade GliomaGlioma, Malignant+2 more
Children's Hospital of PhiladelphiaNCT05553041
Phase 1
Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501
This early phase I trial studies brain tumor (glioma) metabolism in response to eflornithine (DFMO) and polyamine transport inhibitor AMXT-1501 dicaprate (AMXT…
Diffuse GliomaMalignant Glioma
Mayo ClinicNCT05717153