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2,818 recruiting studies matching your filters

Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation

The SPARC study will measure physical activity and functional fitness during cardiac rehabilitation, right after completion of cardiac rehabilitation, and 6 mo…

Cardiac RehabilitationHeart Disease

Estimated

~$10 – $750

Duke UniversityNCT07214350

Prospective Long-Term Outcomes of a Standardized Ross Procedure

This standardized prospective long-term outcome analysis will help reaffirm these findings via a multicenter patient cohort and describe the best practices/tec…

Aortic Valve Disease

Estimated

~$10 – $1,125

Baylor Research InstituteNCT06352671

Observational

A Randomized, Comparative Effectiveness Study of Staged Complete Revascularization With Percutaneous Coronary Intervention to Treat Coronary Artery Disease vs Medical Management Alone in Patients With Symptomatic Aortic Valve Stenosis Undergoing Elective Transfemoral Transcatheter Aortic Valve Replacement: The COMPLETE TAVR Study

Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. Th…

Aortic StenosisCoronary Artery DiseaseCoronary Stenosis

Estimated

~$10 – $6,250

University of British ColumbiaNCT04634240

Phase 1

A Phase 1, Study of Nebulized Matrix - Allogeneic Human Amniotic Fluid (HAF) In Patients With Interstitial Lung Disease: AIRMID Trial

This is a Phase I, pilot clinical trial designed to evaluate the safety and exploratory efficacy of nebulized diluted amniotic fluid, Matrix (HAF-Matrix) in ad…

Lung Diseases, Interstitial

Estimated

~$10 – $8,750

Maule Stem Cell Research Institute, Inc.NCT07372989

An Observational Disease and Clinical Outcomes Registry of Patients With Lysosomal Acid Lipase (LAL) Deficiency

This is an observational, multi-center, international disease registry designed to collect longitudinal data and create a knowledge base that will be utilized …

Lysosomal Acid Lipase DeficiencyCholesterol Ester Storage DiseaseWolman Disease+4 more

Estimated

~$10 – $1,050

Alexion Pharmaceuticals, Inc.NCT01633489

Phase 1

A Phase 1/2 Study to Evaluate Safety, PK and Biodistribution of an Imaging Agent, 18F-OP-801, After Intravenous Administration to Patients With ALS, Alzheimer's Disease, Multiple Sclerosis, Parkinson's Disease and Healthy Volunteers

This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs. 18F-OP-801 is intended as…

Amyotrophic Lateral Sclerosis (ALS)Parkinson Disease (PD)Alzheimer Disease (AD)+1 more

Estimated

~$10 – $8,750

Ashvattha Therapeutics, Inc.NCT05395624

Phase 3

Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease

CMK-0301 is a multi-site, randomized clinical trial to evaluate the safety and efficacy of \[F-18\]Flornaptitril-PET (F-18 FNT-PET) for the prediction of clini…

Alzheimer DiseaseChronic Traumatic Encephalopathy

Estimated

~$10 – $8,750

CereMark Pharma, LLCNCT06254469

Phase 2

Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile

This will be a single center, prospective, open-label, randomized, controlled trial comparing Envarsus XR® to twice-daily tacrolimus. The targeted population w…

End Stage Renal Disease

Estimated

~$10 – $7,500

Roberto GedalyNCT03321656

Molecular Analysis of Neuromuscular Disease

In the Congenital Myopathy Research Program at Boston Children's Hospital and Harvard Medical School, the researchers are studying the congenital myopathies (n…

Central Core DiseaseCentronuclear MyopathyCongenital Fiber Type Disproportion+5 more

Estimated

~$10 – $750

Boston Children's HospitalNCT00272883

Observational

A Pilot Randomized Controlled Trial to Determine the Biochemical Effect, Safety and Patient Reported Outcomes of Copper Supplementation in Patients With Cirrhosis

End stage liver disease or cirrhosis is a major cause of mortality in the United States and the world. Other than targeting the underlying cause, such as alcoh…

CirrhosisChronic Liver DiseaseFibrosis+1 more

Estimated

~$10 – $6,250

University of WashingtonNCT07471542

Phase 3

A Phase 3, Randomized, Modified Double-blind, Active-controlled, Parallel-group, 2-arm Study to Investigate the Safety and Immunogenicity of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

The purpose of this study is to measure whether PCV21 vaccine (investigational pneumococcal vaccine) is safe and can help the body to develop germ-fighting age…

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

The goal of the current study is to conduct a pilot study to test a new version of the handheld OCT device capable of auto-alignment to image the retina in adu…

Eye DiseasesRetinal DiseaseGlaucoma+1 more

Estimated

~$10 – $6,250

Duke UniversityNCT06841575