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2,803 recruiting studies matching your filters

Improving Cardiovascular Health in Veterans With PTSD by Treating Trauma-Related Nightmares With NightWare

The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans…

Post-traumatic Stress Disorder (PTSD)Cardiovascular DiseasesAutonomic Dysfunction+4 more

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT06419959

Generation of Induced Pluripotent Stem (iPS) Cell Lines From Somatic Cells of Participants With Eye Diseases and From Somatic Cells of Matched Controls

Background: \- Best Vitelliform Dystrophy (Best disease), Late-Onset Retinal Degeneration (L-ORD), and Age-Related Macular Degeneration (AMD) all affect the r…

Retinal DiseaseAMDRetinal Degeneration+1 more

Estimated

~$10 – $675

National Eye Institute (NEI)NCT01432847

Phase 3

A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes

The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in people wit…

Metabolic Dysfunction-Associated Steatotic Liver Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07165028

Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

The research goal of this study is to obtain CD34+ hematopoietic stem cells (HSC) from peripheral blood and/or bone marrow, and Mononuclear Cells (lymphocytes …

GranulomaGranulomatous Disease, ChronicLeukocyte Disease+2 more

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001405

Phase 4

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Dupilumab on Airway Inflammation Through Assessments of Mucus Plugging and Other Lung Imaging Parameters in Patients With Chronic Obstructive Pulmonary Disease.

LPS18583 is a multinational, randomized, double-blind, placebo-controlled, parallel-group, Phase 4 study with 2 treatment groups. The purpose of this study is …

Chronic Obstructive Pulmonary Disease

A Phase II Study of Saruparib in Patients With Platinum-Sensitive, HRDsig+ Solid Tumors

The main purpose of this study is to study the effect of saruparib, an experimental PARP inhibitor, on tumors that have an Homologous Recombination Deficiency …

Malignant Neoplastic Disease (Disorder)

Estimated

~$10 – $6,250

Abramson Cancer Center at Penn MedicineNCT07832630

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations

This study will determine whether patients who have been infected with the Lyme bacteria, Borrelia burgdorferi, and treated with antibiotics still have the bac…

Lyme Disease

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001539

Phase 3

A Master Protocol for a Phase 3, Multicenter, Open-label, Long-term Extension Study to Evaluate the Long-term Efficacy and Safety of Mirikizumab in Children and Adolescents With Moderate-to-severe Ulcerative Colitis or Crohn's Disease

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (…

Ulcerative ColitisUlcerative Colitis ChronicInflammatory Bowel Diseases+1 more

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT04844606

Observational

Confirmation of Values and Preferences When Considering a Musculoskeletal Diagnostic Test: A Scenario-Based Study

The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon prob…

Non-traumatic Musculoskeletal ConditionsCarpal Tunnel Syndrome (CTS)Lateral Epicondylitis+5 more

Estimated

~$10 – $6,250

University of Texas at AustinNCT07158892

A Clinical and Genetic Investigation of Pituitary and Hypothalamic Tumors and Related Disorders

There is a variety of tumors affecting the pituitary gland in childhood; some of these tumors (eg craniopharyngioma) are included among the most common central…

PanhypopituitarismGigantism/AcromegalyProlactinoma+1 more

Estimated

~$10 – $675

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT00001595

Phase 2

A Phase 2, Multicenter, Randomized, Open-Label, Active-Controlled Study to Investigate LY4395089/Mirikizumab Co-administration Compared With Mirikizumab in Adults With Moderately to Severely Active Crohn's Disease

The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089), given together with mirikizumab compa…

Crohn Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07483099

Human Biospecimen Procurement and Analysis to Support Translational Research to Identify Genetic Etiology and Disease Mechanism(s) in Rare Genetic Vascular/Cardiovascular Diseases

Background: Studies show that rare genetic variants might lead to diseases. Researchers want to collect blood and tissue samples so they can study them and be…

Undiagnosed DiseasesCardiovascular Disease

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT02543996