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2,803 recruiting studies matching your filters

Integrated Prospective and Retrospective Observational Study to Characterize Biomarkers and Disease Progression in Patients With Pelizaeus-Merzbacher Disease

The purpose of the study is to prospectively assess longitudinal changes in proteolipid protein 1 (PLP1) protein, disease-related biomarkers in cerebral spinal…

Pelizaeus-Merzbacher Disease

Estimated

~$10 – $1,050

Ionis Pharmaceuticals, Inc.NCT05659901

Phase 1

Phase 1b/2a Prospective, Open Label, Multicenter, Two-Arm Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With Immunoglobulin G4-Related Disease

ACE1831 is an off-the-shelf, allogeneic gamma delta T (gdT) cell therapy derived from healthy donors, that is under investigation for the treatment in subjects…

IgG4 Related Disease

Estimated

~$10 – $8,750

Acepodia Biotech, Inc.NCT07061938

Observational

Improving Veteran Referral to Cardiac Rehabilitation: A Hybrid Effectiveness-Implementation Trial

This study will test whether the Veterans Cardiac Rehabilitation Referral Program (VCR2P) improves cardiac rehabilitation participation by studying 816 Veteran…

Cardiovascular DiseaseCardiac Rehabilitation

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07079358

Observational

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD)

IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the…

Chronic Kidney Disease(CKD)Type 2 DMType 2 Diabetes Mellitus (T2DM)

Estimated

~$10 – $6,250

Duke UniversityNCT06906627

Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections From Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation

Bone marrow transplants (BMT) are one form of treatment for disorders of the blood, including leukemia. However, because the procedure is often associated with…

Graft-Versus-Host DiseaseGraft-versus-leukemiaDonor Apheresis

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT00001529

Observational

Revamping Exercise Assessments in Child Health (Project REACH)

This study is a cooperative investigation funded by the NIH. The project is a collaboration among three major NIH Clinical Translational Science Awardees: 1) U…

Cystic FibrosisSickle Cell DiseaseSARS CoV 2 Infection

Estimated

~$10 – $6,250

University of California, IrvineNCT05359991

Observational

Risk Evaluation With AI-CPA + HCS For Patients IN Whom Calcium is confirmEd to Improve Coronary Artery Disease Care

REFINE-CAC is a prospective, multi-center trial assessing the management of asymptomatic participants with CAC scores 1-299 Agatston units or incidental CAC fi…

CAD - Coronary Artery Disease

Estimated

~$10 – $8,750

HeartFlow, Inc.NCT07853716

Observational

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 2) (IRIS-CKD)

IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with typ…

Chronic Kidney Disease(CKD)Type 2 DMType 2 Diabetes Mellitus (T2DM)

Estimated

~$10 – $6,250

Duke UniversityNCT06906640

Cardiovascular Disease Discovery Protocol

Background: \- Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at…

Metabolic DiseaseObesityLi-Fraumeni Syndrome+3 more

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT01143454

Phase 1

A Phase 1, Open Label, Parallel Group Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics of Ribupatide in Healthy Participants and in Participants Living With Severe Renal Impairment or End Stage Kidney Disease

The primary objective of the study is to estimate the PK parameters of ribupatide in participants with severe renal impairment or end-stage kidney disease (ESK…

End Stage Renal DiseaseRenal ImpairmentObesity+1 more

A Phase 2 Platform Basket Study Evaluating Advanced Therapies in Subjects With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

Crohn's disease (CD) and Ulcerative colitis (UC) are 2 types of inflammatory bowel diseases which cause long-lasting, severe inflammation (redness, swelling) i…

Crohn's DiseaseUlcerative Colitis

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program to Evaluate the Efficacy and Safety of Tulisokibart in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. Study 1…

Crohn's Disease

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06430801