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2,803 recruiting studies matching your filters

A Phase 1, Open-label, Single Arm Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Saroglitazar Magnesium Dosed on Alternate Days in Subjects Having Moderate Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Evaluating Pharmacokinetic and safety of Saroglitazar Magnesium 1 mg when dosed on alternate days in subjects having moderate hepatic impairment with cirrhosis…

Cholestatic Liver Disease

Estimated

~$10 – $8,750

Zydus Therapeutics Inc.NCT06825559

Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy

This prospective, non-blinded, single-center, translational research study aims to validate a multimodal advanced imaging exam for cardiac viability. The proto…

Coronary Artery DiseaseCoronary Artery Bypass Graft (CABG)

Estimated

~$10 – $750

University of Texas Southwestern Medical CenterNCT06814587

Phase 1

A Phase 1, Open-Label Extension Groups Study in Subjects Having Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

A Phase 1, Open-label Extension Groups Study in Subjects having Hepatic Impairment with Cirrhosis due to Cholestatic Liver Disease

Hepatic ImpairmentCirrhosisCholestatic Liver Disease

Estimated

~$10 – $8,750

Zydus Therapeutics Inc.NCT05045482

Phase 3

A Phase 3, Multicenter, Randomized, Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Mosliciguat in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease

A Phase 3, Multicenter, Randomized, Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Mosliciguat in Participants with Pulmo…

Pulmonary HypertensionInterstitial Lung DiseaseVascular Diseases+2 more

Estimated

~$10 – $8,750

Pulmovant, Inc.NCT07816185

Phase 2

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamic Effects of ALN-ANG3 in Participants With Diabetic Kidney Disease

This study is researching an experimental drug called ALN-ANG3 (called "study drug"). The study is focused on participants who have diabetic kidney disease. T…

Diabetic Kidney Disease (DKD)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07271186

OPERA Longitudinal Observational Database in the Study of Chronic Diseases, Treatments and Outcomes

Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of…

Chronic DiseaseHIV/AIDSLiver Diseases+4 more

Evaluation of Dementia Education and Resources for Action

The goal of this intervention trial is to evaluate the effectiveness the online training program Dementia Education and Resources for Action (DERA) in improvin…

Alzheimer's Disease and Related Dementia

Estimated

~$10 – $6,250

George Mason UniversityNCT07545577

Phase 2

Endocardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment: A 26-Week (With 26 Week Extension) Phase 2b Randomized, Multi-Center, Double-Blind, Sham Controlled Study to Evaluate Efficacy and Safety

This is a two-part study, comprised of an initial open-label run-in phase (Part 1) in a subset of 3 subjects to provide first data regarding safety, and feasib…

Refractory AnginaCoronary Artery Disease

Estimated

~$10 – $8,750

XyloCor Therapeutics, Inc.NCT07048808

Observational

Feasibility and Acceptability of a Mobile Application "SUPPORT-T" to Increase Equitable Access to Palliative Care in Patients With Progressive Pulmonary Fibrosis (PPF) and Their Caregivers

This pilot randomized controlled trial evaluates the feasibility, acceptability, and accessibility of SUPPORT-T, a digitally delivered palliative care interven…

Progressive Pulmonary FibrosisInterstitial Lung Disease

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT07269262

Blood Amyloid, Tau, and Neurodegeneration Biomarkers and Prediction of Clinical Onset, Cognitive Decline, and Dementia Diagnosis

The purpose of this study is to determine the relationships between amyloid, tau, and neurodegeneration biomarkers in the blood and the presence of Alzheimer's…

Alzheimer DiseaseMild Cognitive ImpairmentDementia

Estimated

~$10 – $750

Washington University School of MedicineNCT06547099

Observational

Personalizing Post Surgical Thromboprophylaxis for Patients With Peripheral Artery Disease

The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peri…

Peripheral Arterial Disease (PAD)AmputationThrombosis+4 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07613840

Phase 1

A Phase I Randomised, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD1613 Following Multiple Ascending Dose Administration in Participants With Autosomal Dominant Polycystic Kidney Disease

A study to investigate safety, tolerability, and pharmacokinetics of AZD1613 following subcutaneous or intravenous administration in participants with autosoma…

Autosomal Dominant Polycystic Kidney Disease

Estimated

~$10 – $7,500

AstraZenecaNCT07228364