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2,802 recruiting studies matching your filters

A Phase 1/2, First-in-Human, Open-Label, Dose Escalation and Expansion Study of STAR0602, a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule, in Subjects With Unresectable, Locally Advanced, or Metastatic Solid Tumors That Are Antigen-rich (START-001)

This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in co…

Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more

Estimated

~$10 – $8,750

Marengo Therapeutics, Inc.NCT05592626

Observational

Autus Size-Adjustable Valve for Surgical Pulmonary Valve Replacement Continued Access Study

Prospective, single-arm, multi-center, continued access study of the Autus Size-Adjustable Valve in pediatric patients aged 18 months to 16 years requiring sur…

Congenital Heart Disease

Estimated

~$10 – $7,500

Edwards LifesciencesNCT07466745

OPN Balloon for SAFE Recanalization of Calcified Coronary Lesions (OPEN-SAFE Registry)

The goal of the OPEN-SAFE registry is to describe the contemporary use and outcomes of SIS-OPN in North America.

Coronary Arterial Disease (CAD)In Stent RestenosisCalcified Coronary Lesions

Estimated

~$10 – $750

Minneapolis Heart Institute FoundationNCT07646444

Phase 2

Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

Background: In non-alcoholic fatty liver disease (NAFLD), fat accumulates in the liver and can cause damage. Researchers want to learn what causes the damage …

Non-Alcoholic SteatohepatitisNon-Alcoholic Fatty Liver Disease

Estimated

~$10 – $5,625

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT03884075

Risk Stratification of Ischemic and Non-ischemic Cardiomyopathies in Racial and Ethnic Minority Groups in the Bronx - Cardiovascular Multimodality Imaging Study

Determining the etiology of cardiomyopathy is of high clinical importance for optimal treatment strategy and prediction of prognosis. There is increased risk f…

Non-ischemic CardiomyopathyCardiomyopathiesHypertrophic Cardiomyopathy+7 more

Estimated

~$10 – $750

Montefiore Medical CenterNCT06610019

Phase 2

Multicenter Trial to Evaluate the Safety and Effectiveness of the Cardiohelp System for up to 30 Days of Support in Children With Severe Cardiac Failure

There are two primary goals of this multicenter clinical trial that combines an FDA device trial and a phase II drug trial in the same study cohort. These two …

Heart FailureCardiogenic ShockCongenital Heart Disease+1 more

Estimated

~$10 – $6,250

Stanford UniversityNCT06080074

Phase 2

Accelerating Breakthrough Targeted New Therapies for Cardio-Renal Complications in People With T1D (Precision T1D Platform)

Breakthrough T1D has awarded support for a joint University of Michigan-Oregon Health \& Science University Center of Excellence (CoE) to address cardio-renal …

Type 1 DiabetesT1D Heart FailureCardio-renal Vascular Function and Failure+1 more

Estimated

~$10 – $6,250

Oregon Health and Science UniversityNCT07594145

Phase 4

Imaging Biomarkers of Freezing of Gait Response to Deep Brain Stimulation

For this study, the investigators are recruiting 54 individuals with Parkinson's Disease and Freezing of Gait (FOG) who are planning to undergo Deep Brain Stim…

Freezing of Gait Symptoms in Parkinson's DiseaseDeep Brain Stimulation

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT06951906

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

This prospective mixed-method interview study aims to qualitatively describe the beliefs, attitudes, and informational needs around gene therapy for rare pedia…

Sickle Cell Disease

Estimated

~$10 – $750

St. Jude Children's Research HospitalNCT05810181

Evaluation of Patients With Gastrointestinal Disease

Background: Ongoing and future research projects that study gastrointestinal diseases depend on access to biological samples and clinical data. Researchers wa…

Lower GI DiseaseGastrointestinal Diseases

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05041374

Phase 2

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Clinical T1-2N0 ER+ Her2- Breast Cancer With Ultrasound Detected Nodal Metastases

The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy pr…

Breast CancerAxillary Nodal DiseaseFemale Breast Cancer+3 more

Estimated

~$10 – $7,500

Alice ChungNCT06092892

Phase 2

A Phase 2A, Open-Label Single Arm Multicenter Exploratory Study to Evaluate the Safety, Tolerability, and Efficacy of Oral Doses of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH).

This study evaluates the effect of ROC-101 in adults with either Pulmonary Arterial Hypertension (PAH) or Pulmonary Hypertension Associated with Interstitial L…

Pulmonary Arterial Hypertension (PAH)Pulmonary Hypertension, Interstitial Lung Disease

Estimated

~$10 – $8,750

AllRock Bio, Inc.NCT07175038