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2,802 recruiting studies matching your filters

Optimize Pediatric OCT (Optical Coherence Tomography) Imaging: a Pilot Study

Handheld optical coherence tomography (OCT) has become an important imaging modality to evaluate the pediatric retina. The objective of this pilot study is to …

Retinal DiseaseGlaucomaOptic Nerve Diseases

Estimated

~$10 – $750

Duke UniversityNCT06139523

Cardiac Clearance vs G60 Hip Frailty Index in Trauma

The primary objective of this study is to establish a data repository that will be permissive of quality improvement studies/observations specific to postopera…

Cardiac Disease

Estimated

~$10 – $750

Methodist Health SystemNCT07490184

Observational

Virtual World-based Cardiac Rehabilitation to Improve Cardiovascular Health and Outcomes Among Cardiac Patients: A Multicenter Randomized Clinical Trial Protocol (Destination Cardiac Rehab Study)

The purpose of this research is to compare health outcomes and participation between a virtual world cardiac rehabilitation (Destination Cardiac Rehab) program…

Heart Diseases

Estimated

~$10 – $6,250

Mayo ClinicNCT07745894

Phase 2

A Multisite, Double-blind, Randomized Controlled Trial Comparing Body Composition, Muscle, and Bone Changes to TestosteRone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial

Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture …

Spinal Cord InjurySpinal Cord InjuriesInjuries, Spinal Cord+11 more

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07742553

Phase 4

INSIGHT-IBD Pragmatic Study: Investigation of Mirikizumab in Real World Settings for Mirikizumab

The goal of this study is to evaluate the real-world effectiveness of treatments for inflammatory bowel disease (IBD) within routine clinical practice. The st…

Ulcerative Colitis (UC)Crohn Disease (CD)

Estimated

~$10 – $7,500

Specialty Networks Research.NCT07686757

Phase 4

The Effectiveness of Systane PRO Preservative Free Verses Blink Triple Care Preservative Free in Providing Relief From Multiple Symptoms of Dry Eye Disease, and Its Impact on Daily Functioning and Overall Comfort in Dry Eye Subjects

The goal of this investigational study is to determine if Systane PRO Preservative Free is non-inferior to BLINK TRIPLE CARE in the clinically significant impr…

Dry Eye Disease (DED)

Estimated

~$10 – $7,500

Gordon Schanzlin New VisionNCT07745062

Phase 3

A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of Acoramidis for Transthyretin Amyloidosis Prevention in the Young (ACT-EARLY Trial)

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque-like subs…

AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+3 more

Estimated

~$10 – $8,750

Eidos Therapeutics, a BridgeBio companyNCT06563895

MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

Recent studies have has shown that magnetic resonance spectroscopy (MRS) can provide validated neuronal markers in patients with Type 1 GD (GD1) who are on sta…

Gaucher Disease, Type 3

Estimated

~$10 – $750

University of MinnesotaNCT05586243

Phase 3

exPDite-2: A Phase 3 Study to Assess the Efficacy and Safety of Midbrain Dopaminergic Neuronal Cell Therapy (Bemdaneprocel) for Participants With Parkinson's Disease

Study BRT-DA01-301 is a Phase 3 multicenter, randomized, sham surgery-controlled, double-blind study to assess efficacy and safety of bemdaneprocel in approxim…

Parkinsons Disease (PD)

Estimated

~$10 – $8,750

BlueRock TherapeuticsNCT06944522

Autoimmune Features of Neurodegenerative Disorders

This study is being conducted to better understand the role of inflammation in Parkinson's disease (PD) and Alzheimer's disease (AD). The investigators plan to…

Parkinson DiseaseAlzheimer DiseaseMild Cognitive Impairment

Estimated

~$10 – $750

Columbia UniversityNCT04239079

Observational

Randomized, Open Label Study to Examine the Outcomes of Physiologic Insulin Resensitization in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus

The purpose of this research is to evaluate outcomes of physiologic insulin re-sensitization (PIR) in patients with Chronic Kidney Disease (CKD) and Type 2 Dia…

Chronic Kidney Disease (Stages 4 and 5)Kidney DiseaseType 2 Diabetes

Estimated

~$10 – $7,500

Well Cell GlobalNCT07187479

Phase 1

Nucleoside Therapy in Patients With Telomere Biology Disorders

The goal of this clinical trial is to learn if a combination therapy of deoxycytidine (dC) plus deoxythymidine (dT) is safe in patients with telomere biology d…

Telomere Biology DisordersDyskeratosis CongenitaRevesz Syndrome+4 more

Estimated

~$10 – $8,750

Suneet AgarwalNCT06817590