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2,801 recruiting studies matching your filters

Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries

This study will test whether using ultrasound imaging within blood vessels during minimally invasive treatment of leg arteries in patients with peripheral arte…

Peripheral Arterial DiseaseLower Extremity Arterial Disease

Estimated

~$10 – $7,500

Baylor Research InstituteNCT07353905

OsseoFit Stemless Shoulder System (Anatomic) Post-Market Clinical Follow-up Study

The purpose of this clinical research protocol is to evaluate the safety, efficacy, and long-term outcomes of the OsseoFit Stemless Shoulder System (Anatomic) …

Shoulder InjuriesShoulder PainShoulder Fractures+2 more

Estimated

~$10 – $1,125

Zimmer BiometNCT07421245

Phase 1

Low-Dose Radiotherapy for Alzheimer's Disease: A Phase I/II Open-Label Feasibility and Safety Study (LDRT-MIND Trial)

To evaluate the safety and tolerability of low-dose whole brain radiotherapy (WBRT) delivered as an induction course of 0.3 Gy × 10 fractions (3.0 Gy total) fo…

Alzheimer DementiaDementiaAlzheimer Dementia (AD)+2 more

Estimated

~$10 – $7,500

Evan ThomasNCT07693140

Natural History and Genetics of VEXAS Syndrome and Related Autoinflammatory Syndromes

This is an exploratory natural history protocol that will enroll patients with known genetic diseases, such as VEXAS syndrome, or as yet undiagnosed disorders …

VEXAS SyndomeAutoinflammatory DiseaseAutoimmune Disease+1 more

Estimated

~$10 – $1,125

NYU Langone HealthNCT06004349

Phase 2

A Phase II Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease

The study is a Phase II clinical trial. Patients will receive intensity modulated total body irradiation (TBI) at a dose of 3 Gy with standard fludarabine/ i.v…

Sickle Cell Disease

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT03121001

Phase 1

Pilot Trial of Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

This phase I trial tests the safety and side effects of leflunomide in combination with steroids in treating patients with acute graft versus host disease who …

Acute Graft Versus Host DiseaseHematopoietic and Lymphoid System Neoplasm

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT05443425

Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease

This is a cross-sectional study in patients with Type 1 diabetes (TID) and chronic kidney disease (CKD) to test if time in range (TIR) affects the degree of hy…

Chronic Kidney Disease(CKD)Type 1 Diabetes (T1D)

Estimated

~$10 – $750

The Cleveland ClinicNCT06694558

Phase 1

A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Two-Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Two Doses of ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)

This study is researching an experimental drug called ALN-CIDEB, also referred to as "study drug". The study is focused on participants with metabolic dysfunct…

Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT06836609

Phase 4

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

The goal of this research study is to evaluate the pathophysiologic mechanisms by which genetic variation impacts response to an FDA-approved medication common…

Genetic PredispositionMetabolic DiseasesType 2 Diabetes

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06003153

Phase 2

A Phase 2, Randomized, Double-blinded, Placebo-controlled Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)

The purpose of this study is to evaluate the safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of efimosfermin in participants with metabol…

Metabolic Dysfunction-Associated SteatohepatitisNon-alcoholic Fatty Liver Disease

Estimated

~$10 – $7,500

GlaxoSmithKlineNCT06920043

Observational

ENGAGE-D: Designing Care Management for Hospice Transitions for Persons Living With Advanced Dementia

This study will test a care management intervention to guide end-of-life care and hospice transitions for persons with dementia and their care partners receivi…

Alzheimer Disease and Related Dementias

Estimated

~$10 – $6,250

New York UniversityNCT07182357

Observational

Frequent Standardized Oral Care Using Human Milk to Prevent Oral Dysbiosis and Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit

Premature infants are susceptible to complications related to infrequent and non-standardized oral care. Although the benefits of frequent standardized oral ca…

Ventilator Associated PneumoniaBronchopulmonary DysplasiaRespiratory Disease

Estimated

~$10 – $6,250

University of FloridaNCT06000761