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651 recruiting studies matching your filters

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Diabetic kidney disease and cardiovascular disease remain the leading causes of morbidity and mortality in people with type 1 diabetes and are exacerbated with…

Type 1 DiabetesDiabetic Kidney DiseaseCardiovascular Diseases+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Kalie TommerdahlNCT05065372

Abbott Structural Heart Device Registry

The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.…

Heart DiseasesASD - Atrial Septal DefectVSD - Muscular Ventricular Septal Defect+3 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Abbott Medical DevicesNCT06590467

Phase 2

The Effects of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals (NAUTICAL)

Black individuals are more likely to have decreased insulin sensitivity which results in a high risk for the development of cardiometabolic disease. The reason…

Diabetes MellitusCardiovascular DiseasesInsulin Sensitivity/Resistance+4 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Alabama at BirminghamNCT04055428

Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert

MicroPort Orthopedics Inc. (MPO) plans to market the EVOLUTION® NitrX™ Non-Porous Keeled Tibia and EVOLUTION® NitrX™ CS/CR Non-Porous Femur with the EVOLUTION®…

Joint DiseasesOsteoarthritisArthritis Knee+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

MicroPort Orthopedics Inc.NCT04816773

Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation

Optimal diagnostic management and underlying pathophysiological mechanisms of selective fetal growth restriction (sFGR) in monochorionic diamniotic (MCDA) twin…

Twin; Pregnancy, Affecting Fetus or NewbornFetal Growth RetardationTwin Monochorionic Diamniotic Placenta+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Leiden University Medical CenterNCT05952583

Molecular Neurosurgical Tissue Bank

The Molecular Neurosurgical Tissue Bank will function as a tissue or specimen repository for biopsy specimens from patients (both adult and pediatric) undergoi…

Brain Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT00593203

Phase 4

Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

It is hypothesize that patients with clinically diagnosed neurodegenerative diseases will have significantly different receptor occupancy of 5HT2A receptors co…

Neurodegenerative DiseasesParkinson DiseaseParkinson Disease Psychosis

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT05357612

Comparative Autoantibody and Immunologic Cell Marker Study

The purpose of this study is to compare immune phenotype, function, and specificity of B lymphocytes from different developmental stages in autoimmune patients…

Autoimmune DiseasesLupus Erythematosus, SystemicCommunicable Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

Emory UniversityNCT02422875

Observational

PhillyCEAL: Addressing Disparities in Chronic Disease Self-management Through an Enhanced Community Health Worker Program

Cardiovascular disease (CVD) disproportionately affects racial/ethnic minorities and underserved populations in Philadelphia. This study aims to evaluate the e…

DisparitiesCommunity Health WorkersCardiovascular Diseases+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT06732102

Phase 2

Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway

This study investigates the potential of vericiguat, a soluble guanylate cyclase stimulator, to improve cardiometabolic health in obese Black individuals with …

Cardiovascular DiseasesInsulin Sensitivity/ResistanceMetabolic Disease+3 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Alabama at BirminghamNCT06320951

Extracellular Vesicle Signaling in Obesity and Cardiometabolic Disease (EVOC)

The goal of this observational study is to research the impact of molecular signals from the heart, liver and fat tissue on cardiovascular disease risk, and th…

Cardiovascular Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT06408961

Phase 1

Retinal Vasoreactivity is a Marker for Cerebral Small Vessel Disease Progression

Cerebral small vessel disease (SVD), present in 80-94% of adults over age 65 years, increases the risk of stroke by 2-fold, and dementia by 2.3-fold. There is …

Cerebral Small Vessel DiseasesCerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and LeukoencephalopathyCerebral Microbleeding+1 more

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Mayo ClinicNCT04753970