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651 recruiting studies matching your filters

A Phase 2 Posology Study With Long-Term Extension in Participants With Well-Controlled Recurrent Pericarditis to Evaluate the Efficacy and Safety of Transition Regimens to KPL-387 Monotherapy From Standard Therapies

The primary objective of this study is to characterize the efficacy and safety of dosing regimens used to transition from prior pericarditis therapies to KPL-3…

Recurrent PericarditisHeart DiseasesPericarditis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Kiniksa Pharmaceuticals International, plcNCT07288216

Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for the Treatment of Crohn's Disease or Ulcerative Colitis

This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells f…

Inflammatory Bowel Diseases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05003947

Observational

Randomized Trial of Endoscopic Ultrasound Examination Using EndoSound Vision System vs. Standard Echoendoscope

This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastroint…

Pancreatic DiseasePancreatic CancerPancreatic Cyst+6 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Orlando Health, Inc.NCT06340620

Observational

A Randomized Placebo-procedure Controlled Trial of the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System PULmonary Artery Denervation Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

The goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiof…

Pulmonary HypertensionHeart Failure With Reduced Ejection FractionHypertension+5 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Pulnovo Medical, Inc.

Observational

Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication

The study is a 2-arm randomized controlled trial among patients referred for kidney transplant evaluation at a single transplant center to compare the effects …

End-Stage Renal DiseaseChronic Kidney DiseasesKidney Transplant+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

State University of New York at BuffaloNCT07072767

Phase 3

A Phase III Crossover Study to Evaluate Bolus Versus Continuous Infusion of Lumason® in Patients With Suboptimal Unenhanced Echocardiography

A phase III study designed as a randomized, within-patient comparison of continuous infusion of diluted Lumason® versus the bolus administration of undiluted L…

Heart Diseases

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Bracco Diagnostics, IncNCT06400004

Observational

Global Pilot Study of rEnal and Hepatic coMbINed denervatIon in Subjects With Uncontrolled Hypertension With and Without High Cardiovascular Risk

The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure …

HypertensionVascular DiseasesCardiovascular Diseases+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic VascularNCT06907147

Observational

Impact of SMART GOAL Setting Protocol on Body Weight and Metabolic Parameters in Children and Adolescents With Prediabetes; a Randomized Clinical Trial.

The goal of this study is to compare the impact of a SMART ((specific, measurable, attainable, realistic, or timely) Goal setting protocol on body weight, meta…

PreDiabetesAdolescent ObesityBehavior, Health+3 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Northwell HealthNCT06067451

Phase 1

Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of…

HypertensionCardiovascular Diseases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of MinnesotaNCT06507657

Real-world Clinical Outcomes in Medicare Patients With Hypertension Treated With Symplicity Renal Denervation Plus Standard of Care Versus Standard of Care in Integrated EHR and Claims Data

This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypert…

HypertensionCardiovascular DiseasesVascular Diseases

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic VascularNCT07174622

Phase 2

A Study to Evaluate the Long-term Safety and Efficacy of Long-acting Antibodies as Single Agents and in Combinations in Participants With Inflammatory Bowel Disease

This is a multicenter, long-term extension (LTE) study in participants with ulcerative colitis (UC) from Study SPY123-201 (The SKYLINE-UC study).

Ulcerative ColitisInflammatory Bowel DiseasesColitis+1 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Spyre Therapeutics, Inc.NCT07652294

Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Background: During a transplant, blood stem cells from one person are given to someone else. The cells grow into the different cells that make up the immune s…

Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System Diseases+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04339777