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8 recruiting studies matching your filters

Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

This protocol is designed to provide a mechanism for the Department of Transfusion Medicine, Clinical Center to collect and process blood components from paid,…

Blood DonorsResearch SubjectsApheresis

Estimated

~$10 – $675

National Institutes of Health Clinical Center (CC)NCT00001846

Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections From Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation

Bone marrow transplants (BMT) are one form of treatment for disorders of the blood, including leukemia. However, because the procedure is often associated with…

Graft-Versus-Host DiseaseGraft-versus-leukemiaDonor Apheresis

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT00001529

Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation, Cellular Therapy, or Gene Therapy

Background: People who have had an allogeneic hematopoietic stem cell transplant (HCT), cellular therapy (CT), or gene therapy (GT) have bone marrow or an imm…

Cellular Immunotherapy, AdoptiveGenetic TherapyTissue Donors+1 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT03000244

Phase 1

Pilot Study of Haploidentical or Matched Donor Virus-Specific T-cells (Cytomegalovirus (CMV) or Adenovirus (AdV)) to Treat CMV or AdV Reactivation or Disease in Patients After Solid Organ or Hematopoietic Stem Cell Transplantation (HCT)

This trial studies the side effects and how well allogeneic cytomegalovirus-specific cytotoxic T lymphocytes (donor cytomegalovirus \[CMV\] specific cytotoxic …

Allogeneic Hematopoietic Stem Cell Transplantation RecipientCytomegalovirusDonor+2 more

Estimated

~$10 – $7,500

Sumithira VasuNCT03665675

Phase 1

Phase 1 Study of Total Lymphoid Irradiation, Total Body Irradiation, Anti-Thymocyte Globulin and Purified Donor CD34+, T-cell and Recipient T Regulatory Cell Transfusion in Human Leukocyte Antigen Mismatched Living Donor Kidney Transplantation

This study will determine whether a preparatory regimen including total lymphoid irradiation (TLI), total body irradiation (TBI), anti-thymocyte globulin (ATG)…

Living Donor Kidney Transplantation

Estimated

~$10 – $6,250

Stanford UniversityNCT03943238

Phase 1

Exercise-induced Adrenergic Receptor Signaling as an Immune Adjuvant for Allogeneic Cell Therapies

This study aims to improve the treatment of blood cancer by using exercise to collect healthier immune cells from donors. Allogeneic adoptive cell therapy is a…

LeukemiaHematopoetic Stem Cell TransplantationDonor Lymphocyte Infusion+3 more

Estimated

~$10 – $6,250

University of ArizonaNCT06643221

Observational

Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication

The study is a 2-arm randomized controlled trial among patients referred for kidney transplant evaluation at a single transplant center to compare the effects …

End-Stage Renal DiseaseChronic Kidney DiseasesKidney Transplant+1 more

Estimated

~$10 – $6,250

State University of New York at BuffaloNCT07072767

A Biospecimen Collection Study to Facilitate Development of an Ex-Vivo Device Platform for Culture, Immune Assay, and Biobanking of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

Primary Objective: This is a study to investigate the feasibility of harvesting, expanding, and selecting T lymphocytes from cancer patients and healthy volun…

Solid Tumor, AdultHealthy DonorsCOVID-19 Donors

Estimated

~$10 – $1,050

BioCytics, Inc.NCT00571389