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Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pa…
Assessment of Laryngopharyngeal Sensation in Patients With Laryngopharyngeal Disorders
A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders. This stu…
Translaryngeal Vibration for Hyperfunctional Voice Disorders
Contemporary treatments for hyperfunctional voice disorders such as muscle tension dysphonia (MTD) are effective but typically do not restore voice handicap or…
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dyst…
Imaging Genetics of Laryngeal Dystonia
The contribution of genetic risk factors to the development of focal dystonias is evident. However, understanding of how variations in the causative gene expre…
Deconstructing Voice Therapy: Towards Enhanced Communication Outcomes
This research study aims to evaluate the effect of treatment delivery method on voice outcomes over 12 months in people with a primary complaint of a voice pro…
Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures: A Pilot Study
Investigators will assess the usefulness of using ultrasound in office procedures for laryngology interventions. Participants who qualify will be adults who ar…
Central Mechanisms and Treatment Response of Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor
Using a comprehensive approach of clinico-behavioral testing and neuroimaging, the researchers will examine the clinical effects of the extended-release formul…
Phonation Resistance Training Exercises (PhoRTE®) Delivered In-person and Via Telehealth: A Noninferiority Randomized Clinical Trial
This study compares how well voice therapy works when delivered in-person versus through telehealth for older adults with age-related voice problems. Researche…
Towards a Unified System to Classify Treatments for Muscle Tension Dysphonia
The goal of this study is to evaluate if using evidence-based, standard ingredient and target codes from the Rehabilitation Treatment Specification System - Vo…
Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application
Deep Brain Stimulation (DBS) is a neurosurgical procedure used to treat tremors, and dystonia. This study will enroll people who have a form of focal dystonia …
A Pilot Study for a Novel and Personalized Voice Restoration Device for Patients With Laryngectomy
The investigators will conduct a pilot experiment for a novel and personalized method for voice restoration using machine learning applied to surface EMG (sEMG…