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Phase 1
Pharmacogenomic Contribution to the Biotransformation of Trihexyphenidyl and Development of a Precision Dosing Model for Children With Dystonia and Cerebral Palsy
This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is b…
Pediatric DisorderGenetic PredispositionDystonia, Secondary+5 more
Children's Mercy Hospital Kansas CityNCT06554288
Dystonia Genotype-Phenotype Correlation: A Study to Identify Additional Genetic Associations That Contribute to Specific Dystonic Phenotypes
The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brai…
DystoniaDystonia; IdiopathicDystonia, Primary+19 more
University of Texas Southwestern Medical CenterNCT03428009