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A Phase Ib Open Label Clinical Trial to Evaluate the Safety and Efficacy of ERAS-801 in Recurrent Glioblastoma or Elderly Newly Diagnosed Glioblastoma Patients With EGFR Amplification and/or Mutation (ERAS-801-3.0)

This phase Ib trial tests the safety and side effects of ERAS-801 in treating patients with isocitrate dehydrogenase (IDH) wildtype, epidermal growth factor re…

GlioblastomaGlioblastoma, IDH-WildtypeGliosarcoma+3 more

Estimated

~$10 – $6,250

Jonsson Comprehensive Cancer CenterNCT07089641

Phase 2

Randomized Phase II Stereotactic Ablative Radiation Therapy (SABR) for Metastatic Unresected Renal Cell Carcinoma (RCC) Receiving Immunotherapy (SAMURAI)

This phase II trial tests whether the addition of radiation to the primary tumor, typically given with stereotactic ablative radiation therapy (SABR), in combi…

Metastatic Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8+1 more

Estimated

~$10 – $7,500

NRG OncologyNCT05327686

Vonoprazan Pregnancy Registry: An Observational Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

The main objective of the study is to compare the maternal, fetal, and infant outcomes of pregnant women who are exposed to vonoprazan during pregnancy with ou…

Erosive EsophagitisHeartburnSymptomatic Non-erosive Gastroesophageal Reflux Disease+1 more

Estimated

~$10 – $1,050

Phathom Pharmaceuticals, Inc.NCT06660342

Phase 1

A Phase 1 Open-label, Non-randomized, Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

The clinical schedule will consist of 3 injections of CD40.HIVRI.Env (VRIPRO) at weeks 0, 4, and 24.40 volunteers without HIV and in overall good health, aged …

HIV Infections

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT06665646

Observational

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

This study utilizes a randomized controlled trial design to evaluate the efficacy of couples motivational interviewing (MI) to reduce the frequency and severit…

Substance UseHIV Infections

Estimated

~$10 – $6,250

Hunter College of City University of New YorkNCT06307977

Phase 4

Longitudinal Serum and Mucosal RSV Antibodies Following Clesrovimab (Enflonsia™, Merck) Administration in Infants During Their First Respiratory Season or [The EMBRACE Study: Enflonsia™ Monoclonal in Babies - RSV Antibody Concentration Evaluation]

Clesrovimab is an FDA-approved antibody drug recommended for infants younger than 8 months who are entering their first respiratory syncytial virus (RSV) seaso…

RSV Infection

Estimated

~$10 – $6,250

Emory UniversityNCT07824167

Phase 4

A Randomized Controlled Trial of Buspirone for Anxiety in Autistic Youth

The purpose of the study is to do a preliminary trial to determine if buspirone is effective, safe, and tolerable in autistic youth with anxiety.

AnxietyAutism Spectrum Disorder

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07439042

ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE), a Case Collection Registry for 3D Breast Automated Ultrasound Using ATUSA System as Well as Other Breast Imaging Modalities.

AUDIBLE is a multi-site, clinical study conducted in the United States aimed at gathering data on 3D Automated Breast Ultrasound imaging using the iSono Health…

Breast CancerBenign Breast ConditionBreast Fibroadenoma+6 more

Estimated

~$10 – $1,050

iSono Health, Inc.NCT07505797

Phase 1

Erector Spinae Plane Block for Patients With Intractable Abdominal Pain in the Emergency Department: A Pilot Study

Currently, the standard treatment of nonsurgical abdominal pain in the Emergency Department (ED) includes narcotic pain medication. This can be addictive and c…

Erector Spinae Plane Block

Estimated

~$10 – $6,250

University of California, IrvineNCT07826936

Phase 3

A Phase 3, Randomized, Double-blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Engasertib in Subjects With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT)

The primary objective of this trial is to assess the efficacy of engasertib 40 mg once daily (QD) in reducing the frequency of epistaxis compared to placebo QD…

Hereditary Hemorrhagic Telangiectasia

Estimated

~$10 – $8,750

Vaderis Therapeutics AGNCT07743671

Phase 1

A Phase I/II, Multi-site, Open-label, Two-part Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of BNT323 in Combination With BNT327 in Participants With Advanced Breast Cancer

This is a Phase I/II, multi-site, open-label, two-part study designed to evaluate the efficacy, safety, optimized dose and contribution of components of BNT323…

Locally Advanced Breast CancerUnresectable Breast CarcinomaMetastatic Breast Cancer

Estimated

~$10 – $7,500

BioNTech SENCT06827236

Phase 2

PD-1 (Programmed Cell Death Protein 1) Blockade in Mismatch-repair Deficient Colorectal Cancer in Nigeria

The researchers are doing this study to find out whether tislelizumab is an effective treatment for people with colorectal cancer who are living in Nigeria. Th…

Colorectal Cancer

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT06529523