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2,200 recruiting studies matching your filters

A Phase 1/2 Multicenter Study Evaluating the Safety and Efficacy of LYL273 in Patients With Relapsed or Refractory Metastatic Colorectal Cancer

This is a Phase 1/2 open-label, multicenter study evaluating the safety and efficacy of LYL273 in participants with relapsed or refractory metastatic colorecta…

Colorectal Cancer

Estimated

~$10 – $8,750

Lyell Immunopharma, Inc.NCT05319314

Phase 1

A Phase 1b/2, Safety Lead-in and Dose-Expansion, Open Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Activity of Ivosidenib in Combination With Durvalumab and Gemcitabine/Cisplatin as First-line Therapy in Participants With Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

The objective of this study is to investigate the safety, tolerability and preliminary activity of ivosidenib in combination with durvalumab and gemcitabine/ci…

Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Estimated

~$10 – $7,500

Institut de Recherches Internationales ServierNCT06501625

Observational

Neural Mechanisms of Interpersonal Expectations on Negative Affect

The goal of this clinical trial is to learn whether non-invasive brain stimulation, called transcranial temporal interference stimulation (tTIS), can reduce ne…

Negative AffectivityNon-invasive Brain StimulationPlacebo Effect+1 more

Estimated

~$10 – $6,250

Trustees of Dartmouth CollegeNCT06980090

Phase 2

Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery

The goal of this prospective pragmatic randomized clinical trial is to determine if preoperative administration of tranexamic acid (TXA) reduces bleeding durin…

BleedingColorectal DisordersThromboembolism+1 more

Estimated

~$10 – $7,500

Kristen BanNCT06657924

Phase 2

A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome

To learn about the effects of naproxen and aspirin on the normal colon in people with Lynch Syndrome.

T CellsColorectal CancerLynch Syndrome

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05411718

Clinical Microbial Species and Antibiotic Resistance Identification in Patients Presenting to the Emergency Department With Three of Four Systemic Inflammatory Response Syndrome (SIRS) Criteria - is Rapid Identification Possible and Accurate?

The aim of this project is to test the utility of The Gene Z device (as of 2018 Gene Z no longer being used), now using In-Dx and other rapid identification te…

SepsisSystemic Inflammatory Response SyndromeInfection Mixed+5 more

Estimated

~$10 – $750

Michigan State UniversityNCT01904188

Observational

Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs

The objective of the pragmatic trial to test the effectiveness of an existing, ongoing clinical service, the VA National TeleOncology program (NTO), a multilev…

Lung Cancer DiagnosisColorectal Cancer (Diagnosis)Prostate Cancer Diagnosis+1 more

Estimated

~$10 – $7,500

NYU Langone HealthNCT06559059

Phase 3

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures: A Multicenter Randomized Controlled Trial

This is a multi-center, pragmatic, parallel arm randomized controlled trial (RCT) of 352 patients with high-risk open or closed tibial plateau fracture, high-r…

Fracture of TibiaWound HealInfected Wound+2 more

Estimated

~$10 – $7,500

Major Extremity Trauma Research ConsortiumNCT06337292

Phase 1

A Multicenter Open-Label Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.

Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma (PDAC)+1 more

Estimated

~$10 – $8,750

Revolution Medicines, Inc.NCT05379985

Phase 1

A Phase 1, Open-label, Multicenter, Dose-escalation and Cohort Expansion Study of OKN4395, a Triple Antagonist of EP2, EP4, and DP1 Prostanoid Receptors, as Monotherapy and in Combination With Pembrolizumab, in Patients With Advanced Solid Tumors

The purpose of this study is to investigate the study drug, OKN4395, administered alone and in combination with pembrolizumab. The overall objectives of this …

Solid TumoursSarcomaHNSCC+12 more

Estimated

~$10 – $7,500

EpkinNCT06789172

The INCLUDE (INvestigation of Co-occurring Conditions Across the Lifespan to Understand Down Syndrome) Project's Collaboration for Down Syndrome Progress (CDP) Program

The Collaboration for Down Syndrome Progress (CDP) is a long-term study that follows people with Down syndrome of all ages. The goal is to better understand th…

Down SyndromeChromosome DisordersIntellectual and Developmental Disabilities

Estimated

~$10 – $1,125

RTI InternationalNCT07625579

A Prospective Clinical Registry Investigating Outcomes of Elective Robotic Transhiatal Esophagectomy

The primary goal of this study is to collect short-term and long-term health outcomes of a robotic transhiatal esophagectomy procedure. Clinical (or health) ou…

Esophagectomy

Estimated

~$10 – $750

Northwestern UniversityNCT05950438