Find your next paid study

Texas Tech UniversityNCT06055322

Phase 4

Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis

This proposal will examine the effects of estradiol administration on perimenopausal-onset (PO) anhedonia and psychosis symptoms as well as on brain function u…

DepressionPsychosisAnhedonia

University of North Carolina, Chapel HillNCT05282277

Opioid Use DisorderBack PainStress

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

The purpose of this study is to see how stress influences the effects of opioid pain medications often used to help relieve back pain. The study will help to l…

Vanderbilt University Medical CenterNCT05142267

Phase 2

A Randomized, Double-blind, Placebo-controlled Trial of ALTO-207 in Adults With Treatment-resistant Depression

The purpose of this trial is to measure depressive symptoms following treatment with ALTO-207 compared with placebo in participants with TRD.

Treatment-resistant Depression (TRD)

Alto NeuroscienceNCT07553637

~$10 – $7,500

Phase 2

In Vivo Targeting of Neuroactive Steroid and Immune Networks for Depression in People Living With HIV

This study will determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression. Participa…

Major Depressive DisorderAnxiety DepressionHIV

Massachusetts General HospitalNCT05570812

Posttraumatic Stress DisorderPTSD

Changing the Treatment Course: Clinical Trial of Sequenced Interventions to Optimize Treatment for Veterans With PTSD

By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatm…

The University of Texas Health Science Center at San AntonioNCT07176273

Major Depressive Disorder

Confirmatory Efficacy Randomized Clinical Trial of Amygdala Neurofeedback for Major Depressive Disorder

The goal of this study is to evaluate whether rtfMRI-nf training to increase the amygdala response to positive memories may serve as a stand-alone intervention…

Kymberly YoungNCT05703256

~$10 – $7,500

Phase 4

A Randomized, Double-blind, Active-controlled Study of AXS-05 for the Prevention of Relapse of Depressive Symptoms

This is a randomized, double-blind, active-controlled, multi-center study to evaluate the efficacy of AXS-05, compared to bupropion, in preventing the relapse …

Major Depressive Disorder

Axsome Therapeutics, Inc.NCT06223880

~$10 – $8,750

Stepped Care Cognitive Behavioral TherapyExercisePhysical Activity+1 more

Latinas Integrating Fitness and Therapy (LIFT)

Investigators are studying how combining a stepped-care mental health counseling program with an evidence-based exercise program can help Latina cancer survivo…

Colorado State UniversityNCT07223346

Blood Pressure, Body Composition, Immune Function

Evaluating the Effects of a Synbiotic Versus Probiotic or Placebo on Gut Microbiota and Cardiometabolic Health: A Randomized Double-Blind Placebo Controlled Trial

Accordingly, the purpose of this study is to evaluate the efficacy of 1) supplementation with Synbiotic (Plexus® Triplex), 2) commercially-available Probiotic,…

Skidmore CollegeNCT06544915

Major Depressive EpisodeBorderline Personality DisorderSuicide

Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

This neuroimaging study is a clinical trial investigating the effectiveness of intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) to the inf…

Massachusetts General HospitalNCT04130958

Trauma, PsychologicalTrauma and Stressor Related Disorders

Systematic Redesign of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) to Enhance Usability, Engagement, Appropriateness, and Impact in Schools

Trauma-focused cognitive behavior therapy (TF-CBT) has the strongest evidence of any clinical intervention for youth trauma but is rarely adopted in the educat…