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Understanding the Safety of Home Ketamine Treatment Plans for Chronic Conditions
A study aimed to assess the efficacy of the various approaches to prescribing Ketamine currently in use off-label. The focus will be to include ketamine within…
Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder
The purpose of this study is to examine the feasibility and acceptability of an online group Neuro-behavioral Therapy (NBT) with text messaging intervention fo…
Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder
The US is currently going through an opioid crisis, and while Medication Assisted Treatments such as buprenorphine (BUP) have proved highly effective at stabil…
Implementing a Scalable Mental Health Intervention for International Students: A Pilot Study of Digitized Self-Help Plus
The goal of this clinical trial is to learn if an adapted version of Self-Help Plus (SH+), a stress management program developed by the World Health Organizati…
Community-Embedded, Layperson-Supported Digital Mental Health Intervention for Homebound Older Adults With Depression: A Type 1 Hybrid Effectiveness- Implementation RCT
This study is a randomized Type I hybrid effectiveness-implementation trial aimed at evaluating the effectiveness of Empower@Home, an internet-delivered cognit…
Effects of Kinesio Tape on Delayed Onset Muscle Soreness
The purpose of this study is to determine the effect of Kinesio tape on delayed onset muscle soreness of the biceps muscle of your arm following strenuous exer…
Neurobehavioral Effects of Visual Assistive Technologies
The goal of this clinical investigation is to learn how the brain responds when visual information is converted into patterns of sound or touch in blind and si…
Treatment of Stress-Related Psychopathology: Targeting Maladaptive and Adaptive Event Processing
The R33 will be a randomized controlled trial to replicate changes in the targets (unproductive processing, avoidance, reward deficits) from the R61 phase in a…
Using Human Brain Connectivity to Identify the Causal Neuroanatomical Substrate of Depression Symptoms
This study originally included 140 subjects with medication-refractory depression undergoing 10 Hz transcranial magnetic stimulation (10Hz-TMS) to the left dor…
Identifying Biobehavioral Predictors and Targeting Mechanisms of Intervention in Adolescent Posttraumatic Stress Disorder
This study examines how adolescents with trauma-related symptoms respond to stress and strong emotions. The study assesses brain activity, physiological respon…
Effects of Hip Bump Manipulation Versus Sham Treatment on Hip Internal Rotation, External Rotator Strength, and Bipodal Landing in Healthy Adults Aged 18-45: A Single-Blinded Randomized Controlled Trial
The purpose of this study is to objectively assess the effects of hip bump manipulation (HBM) on a healthy population aged 18-45 years. We hypothesize that the…
Effect of Restricted Fluid Management Strategy on Outcomes in Critically Ill Pediatric Trauma Patients: A Multicenter Randomized Controlled Trial
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing f…