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The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function
Black individuals are at increased cardiovascular disease risk. The central goal of the study is to determine if mitochondrial reactive oxygen species influenc…
Maternal Positive Affect Socialization and Child Neural Reward Response
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response…
Low Intensity Focused Ultrasound for Posttraumatic Stress Disorder
The goal of this study is to develop a new, non-invasive brain stimulation modality called low intensity focused ultrasound (FUS) as a psychiatric rehabilitati…
First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands ([18F]ABBV964i and [ 18F]ABBV-965i) as Potential PET Radioligands for Imaging Tau Protein in the Brain of Patients With Probable PSP and Healthy Volunteers
This clinical study is being conducted to learn more about two new imaging drugs, called \[18F\]ABBV-964i and \[18F\]ABBV-965i, which are designed to help doct…
Effect of Raised End-Tidal pCo2 on Choroidal Volume
This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated i…
Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein (NICE-ICP)
Elevated intracranial pressure is a common complication of brain injury which means that the pressure within the skull rises above normal levels. The negative …
Evaluating Evidence Based Options for Initial PTSD Treatment Non-Responders
This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respo…
A Grounded Theory of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis - A Biopsychosocial Approach to Surgical Evaluation and Outcomes.
This study utilizes a grounded theory methodology to explore patient experiences of phrenic nerve reconstructive surgery as a treatment for diaphragmatic paral…
Ready, Set, Nourish Study
This study is about preparing women with excessive weight to have better breastfeeding outcomes. By doing this study, the investigators hope to learn more abou…
Pilot Study to Assess Safety, Tolerability and Efficacy of Virtual Reality in Cancer Patients
This clinical trial tests the safety, tolerability, and effectiveness of a virtual reality intervention to improve psychological symptom burden for cancer pati…
Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship
Intimate partner violence (IPV) is a serious public health problem that results in significant health and economic burdens including mortality, morbidity, and …
Combined Nonpharmacological Therapies for MTBI-Related Headaches
This study will assess the combined effectiveness of repetitive transcranial magnetic stimulation (rTMS) and telehealth based therapy in helping manage mild tr…