Find your next paid study

Merck Sharp & Dohme LLCNCT07705607

Phase 3

A Randomized, Double-Masked, Multicenter, 3-Arm, Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal (IVT) MK-8748 Compared With Aflibercept (2 mg) in Participants With Diabetic Macular Edema (DME)

Researchers are looking for new ways to treat diabetic macular edema (DME). In this trial, researchers want to learn if a trial medicine called MK-8748 can tre…

Diabetic RetinopathyMacular Edema

Merck Sharp & Dohme LLCNCT07705555

Phase 2

Lactiplantibacillus Plantarum 299v Probiotic Probiotic Supplementation in Patients With Diabetic Macular Edema

This pilot prospective, interventional, longitudinal study, aims to evaluate the potential benefits of the probiotic supplement Lactobacillus plantarum 299v in…

Diabetic Macular Edema

Massachusetts Eye and Ear InfirmaryNCT07383701

Phase 1

A First-in-human, Open-label (Part 1), Randomized (Part 2), Phase I/IIa Trial to Study Safety and Tolerability of Multiple Rising Intravitreal Doses of BI 3812465 in Patients With Center-involved Diabetic Macular Edema

This study is open to adults with diabetic macular edema that involves the center of the eye. The purpose of this study is to find out how well different doses…

Diabetic Macular Edema

Boehringer IngelheimNCT07553429

Phase 2

A Randomised, Double-masked, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Oral BI 1815368 in Participants With Centre-involved Diabetic Macular Edema for 48 Weeks of Treatment (THULITE)

This study is open to adults 18 and older with an eye condition called diabetic macular edema. People are required to have a specific type of diabetic macular …

Macular Edema

Boehringer IngelheimNCT06962839

Observational

Perioperative Photobiomodulation With the ELIXIR MD System in Facial Plastic Surgery: A Randomized Controlled Trial

This study is testing whether a new light therapy schedule can reduce bruising after facial plastic surgery, compared with the light therapy schedule currently…

Postoperative Facial EcchymosisPostoperative Facial Edema

Acute Hereditary Angio Edema

Elixir MD IncNCT07846631

Phase 3

Prospective, Multicenter, Randomized, Double-blind, Parallel Group, Placebo- Controlled, Efficacy and Safety Phase 3 Study of an Intravenous Human Plasma- Derived C1 Esterase Inhibitor (C1-INH) Concentrate in Participants With Congenital C1-INH Deficiency for the Treatment and Pre-procedure Prevention of Acute Hereditary Angioedema Attacks

Prospective, multicenter, randomized, double-blind, parallel group, placebo- controlled, efficacy and safety phase 3 study of an intravenous human plasma- deri…

Diabetic Macular Edema (DME)Diabetic Retinopathy

OctapharmaNCT06361537

Phase 4

Corticosteroid for Diabetic Macular Edema (DME) Study

Our current goals include confirming inflammation mediators are biomarkers of DR and DME The Aim of this project is to measure aqueous PGE2 and inflammatory c…

Vanderbilt University Medical CenterNCT07843849

~$10 – $6,250

Phase 2

Lymphedema Prevention Through Immediate Lymphatic Reconstruction (LILY) Trial

To learn if reconstruction of the lymphatic system at the time of axillary lymphadenectomy can reduce the risk of developing lymphedema.

Lymphedema

M.D. Anderson Cancer CenterNCT06989099

~$10 – $6,250

A Prospective Study Comparing Quality of Life in Patients With Lymphedema Who Undergo Surgical Treatment Versus Non-Surgical Management

This study is being done to see the long-term results for patients who choose to have surgery for lymphedema (with the vascularized lymph node transfer), compa…

Lymphedema

Memorial Sloan Kettering Cancer CenterNCT03248310

~$10 – $750

Phase 3

A Phase 3, Randomized, Double-blind, Placebo-controlled, 3-Part Study to Evaluate the Efficacy and Safety of Orally Administered Deucrictibant XR Tablet for Prophylaxis and Deucrictibant Soft Capsule for On-demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

This is a Phase 3, multicenter, 3-part study, with 2 randomized, double-blind, placebo-controlled parts and an open-label extension part, to evaluate the effic…

Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)

Pharvaris Netherlands B.V.NCT07266805

Phase 4

A Phase 4, Open-Label Trial to Evaluate the Safety and Effectiveness of Sebetralstat When Used as Preprocedural Short-term Prophylaxis in Patients With Hereditary Angioedema

This is a Phase 4, prospective, open-label trial to evaluate the safety and effectiveness of sebetralstat when used for STP for a qualifying procedures in pati…

Hereditary Angioedema