The purpose of this retrospective and prospective project is to understand the molecular and genetic basis of liver cancer of childhood. Understanding the mole…

Childhood Liver CancerLiver Malignant TumorsEmbryonal Sarcoma of Liver (Disorder)+3 more

~Estimated

~$10 – $750

University of PittsburghNCT03959800

Phase 1

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using Interleukin-15 And -21 Armored Glypican-3-Specific Chimeric Antigen Receptor Expressing Autologous T Cells

The body has different ways of fighting infection and disease. No single way seems perfect for fighting cancers. This research study combines two different way…

HepatoblastomaHepatocellular CarcinomaWilms Tumor+5 more

~Estimated

~$10 – $6,250

Baylor College of MedicineNCT06198296

Phase 1

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

This Phase 1, open-label, non-randomized study will enroll pediatric and young adult subjects with relapsed or refractory non-central nervous system (CNS) mali…

Solid Tumor (Excluding CNS)Liver Cell CarcinomaMalignant Rhabdoid Tumor+7 more

~Estimated

~$10 – $6,250

Seattle Children's HospitalNCT07148050