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179 recruiting studies matching your filters

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (C…

Lung Cancer (Diagnosis)OsteochondromaSpitz Nevus+14 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT07675967

Observational

Adaptive Daily MR-Guided Adjuvant Pelvic Therapy-Endometrial Cancer: A Phase I/II Feasibility Study

To evaluate the safety, tolerability, and preliminary efficacy of moderately hypofractionated (15-fraction) MR-guided adaptive pelvic IMRT in patients with end…

Endometrial Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Rutgers, The State University of New JerseyNCT07643012

Phase 3

DESTINY-Endometrial01: An Open-Label, Sponsor-Blinded, Randomized, Controlled, Multicenter, Phase III Study of Trastuzumab Deruxtecan (T-DXd) Plus Rilvegostomig or Pembrolizumab vs Chemotherapy Plus Pembrolizumab as First-Line Therapy of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR), Primary Advanced or Recurrent Endometrial Cancer

DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when compared to chemothera…

Endometrial Cancer

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AstraZenecaNCT06989112

Phase 1

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

This is a two-part, open-label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pha…

Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+10 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

858 Therapeutics, Inc.NCT06395519

Phase 2

A Phase 2 Study of Ivonescimab (Bispecific Antibody Against PD1 and VEGF) For the Treatment of Endometrial (EC) and Cervical (CC) Cancers

The researchers are doing this study to find out if ivonescimab is an effective treatment for people with endometrial cancer (EC) and/or cervical cancer (CC). …

Endometrial CancerCervical Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT06925724

Phase 1

Phase 1b/2a Clinical Study of Catequentinib Hydrochloride (AL3818) Monotherapy or Combining Therapy With Other Anti-tumor Agents in Advanced, Metastatic Endometrial, Low Grade Serous Ovarian Cancer (LGSOC), STS or GBM Cancers

This phase 1b/2a study evaluates the investigational oral drug catequentinib hydrochloride (AL3818), given alone or with AL58805, temozolomide, or lomustine (C…

Endometrial NeoplasmsOvarian NeoplasmsSoft Tissue Sarcoma (STS)+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Advenchen Pharmaceuticals, LLC.NCT07811297

Phase 3

A Phase III Randomised Clinical Trial Comparing Sentinel Node Biopsy With No Retroperitoneal Node Dissection in Apparent Early-Stage Endometrial Cancer

Endometrial cancer (EC) is the most common gynaecological cancer. Current treatment of EC typically includes removal of the uterus and to determine the extent …

Endometrial Cancer Stage ISentinel Lymph NodeSurgery

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Queensland Centre for Gynaecological CancerNCT04073706

Phase 2

A Phase II Study of Tailored Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endormetrial Cancer (RAINBO BLUE & TAPER)

This protocol tests de-escalated adjuvant treatment in patients with POLE-mutated or p53wt/NSMP (p53 wildtype/no specific molecular profile) early-stage endome…

Endometrial Cancer

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Canadian Cancer Trials GroupNCT05640999

Phase 1

A Phase 1a/1b, Multicenter, Open-label, Dose Escalation/Expansion, Multiple-dose Study to Evaluate the Safety and Activity of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

A phase 1a/1b, multicenter, open-label, dose escalation/expansion, multiple-dose study to evaluate the safety and activity of DR-0202 in patients with locally …

Triple Negative Breast CancerHER2-negative Breast CancerNon Small Cell Lung Cancer+9 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Dren Bio

cfDNA Assay Multicenter Prospective Observational Validation for Early Cancer Detection, Minimal Residual Disease, and Relapse

This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differenti…

Brain CancerBreast CancerBladder Cancer+17 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Adela, IncNCT05366881

Phase 1

A Pre-Operative Window Study of Tirzepatide in Obesity-Driven Endometrial Cancer

LCCC2415 examines the antiproliferative effect of tirzepatide on the endometrium of endometrial cancer (EC). This is a pre-operative window clinical study. End…

Endometrial CancerObesity

Estimated

~$150 – $3,000

Actual pay is set by the research site.

UNC Lineberger Comprehensive Cancer CenterNCT07065552

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

This study will collect tumor specimens with correlated clinical and demographic data from patients who are undergoing a biopsy or similar procedure to obtain …

CancerImmunotherapyAdvanced Solid Tumors Cancer+12 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

ElephasNCT07327489