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27 recruiting studies matching your filters
Phase 1
A Phase 1/2 Study of Tegavivint (NSC#826393) in Children, Adolescents, and Young Adults With Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come b…
Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more
Estimated
~$10 – $7,500
Children's Oncology GroupNCT04851119
Phase 1
Lurbinectedin in FET-Fusion Tumors (LIFFT)
The purpose of this study is to find out if a drug called lurbinectedin (the "study drug") is safe and effective at treating people with recurrent or relapsed …
Ewing SarcomaDesmoplastic Small Round Cell TumorPediatric Cancer+1 more
Estimated
~$10 – $6,250
Children's Hospital of PhiladelphiaNCT05918640
Phase 1
A Phase I Study of Vorinostat in Combination With Vincristine, Irinotecan, and Temozolomide in Children, Adolescents, and Young Adults With Relapsed or Refractory Solid Tumors and CNS Malignancies
Investigators are testing new experimental drug combinations such as the combination of vorinostat, vincristine, irinotecan, and temozolomide in the hopes of f…
Ewing SarcomaRhabdomyosarcomaWilms Tumor+3 more
Estimated
~$10 – $6,250
New York Medical CollegeNCT04308330