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4 recruiting studies matching your filters

Improving Lung Health in Premature Babies Through Early Nutrition: The More & Early Nutritional Delivery for Bronchopulmonary Dysplasia (MEND-BPD) Trial

This Phase II, parallel-group, masked, randomized clinical trial aims to evaluate whether a DHA/ARA-enriched, fortified human milk diet administered during the…

Extreme PrematurityEnteral NutritionBronchopulmonary Dysplasia

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07307612

Observational

Ventilator Pressure and Optimization of Compliance and Hemodynamics: VPOCH Trial

In preterm infants \< 34 weeks' gestation at birth receiving respiratory support with invasive positive pressure ventilation, the positive end-expiratory press…

Bronchopulmonary DysplasiaPulmonary Hypertension Due to Lung Diseases and HypoxiaExtreme Prematurity+2 more

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06512935

Phase 2

Single-dose Prophylactic INdomethacin in Extremely Preterm Infants - A Multicenter Randomized Blinded Placebo-Controlled Trial (the SPIN RCT)

In Canada, about 900 babies each year are born very early (\<26 weeks of gestation) and have a high chance of dying or having a serious bleed in the brain. Fam…

Extreme PrematurityIntraventricular HemorrhageMorbidity;Newborn

Estimated

~$10 – $6,250

University of British ColumbiaNCT06572917

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis: An International Comparative Effectiveness Research Project

Fluid-unresponsive hypotension needing cardiotropic drug treatment is a serious complication in very preterm neonates with suspected late-onset sepsis (LOS; de…

Late-Onset Neonatal SepsisExtreme PrematurityNeonatal Hypotension

Estimated

~$10 – $750

Mount Sinai Hospital, CanadaNCT05347238