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43 recruiting studies matching your filters

Screening Protocol for the Evaluation and Diagnosis of Potential Research Participants

This study will allow National Eye Institute (NEI) doctors the opportunity to examine people with eye disease, whether the diagnosis is known or not, to determ…

Eye Diseases

Estimated

~$10 – $675

Actual pay is set by the research site.

National Eye Institute (NEI)NCT00655096

Phase 1

A Randomized, Double-Masked, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ETHY-001

The primary objective of study is to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ETHY-001 in healthy volunteers and partici…

Thyroid Eye Disease (TED)Graves' DiseaseEye Diseases, Hereditary+11 more

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Ethyreal Bio, Inc.NCT07885605

Adaptive Optics Retinal Imaging

Background: \- By the time diseases of the retina are detected, serious damage has often already been done. Researchers want to find better ways of viewing th…

Eye DiseasesHealthy Volunteers

Estimated

~$10 – $675

Actual pay is set by the research site.

National Eye Institute (NEI)NCT02317328

Clinical and Molecular Studies in Families With Inherited Eye Disease

Background: Genes are the basic units of heredity. When genes are changed, certain cells don t work like they should. Researchers want to try to better unders…

Inherited Eye Disease

Estimated

~$10 – $675

Actual pay is set by the research site.

National Eye Institute (NEI)NCT02771236

Phase 2

A 12-Week, Phase 2, Multicenter, Randomized, Double-Masked, Vehicle Controlled, Parallel Group Study With 2 Weeks of Follow-Up to Evaluate the Efficacy and Safety of DFL24498 0.08% Topical Ophthalmic Solution Versus Vehicle in Participants With Dry Eye Disease

This is a Phase 2, randomized, multicenter, double masked, vehicle controlled, parallel group study to evaluate the efficacy and safety of DFL24498 topical oph…

Dry Eye Disease (DED)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Dompé Farmaceutici S.p.ANCT07503886

Phase 3

A Double-Masked, Randomized, Placebo-Controlled, Paired-Eye Study to Evaluate the Efficacy, Safety and Tolerability of Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Due to the c.2991+1655A>G (p.Cys998X) Mutation in the CEP290 Gene

The purpose of this double-masked, randomized, placebo-controlled, paired-eye study is to evaluate the efficacy, safety and tolerability of Sepofarsen in subje…

Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Laboratoires TheaNCT06891443

Phase 3

A Phase 3, Randomized, Double-mask, Placebo-controlled Study With Open-label Extension to Evaluate the Efficacy and Safety of Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)

The goal of this clinical trial is to evaluate the efficacy, safety, and tolerability of linsitinib in participants with moderate to severe Thyroid Eye Disease…

Thyroid Eye Disease, TEDGraves Orbitopathy

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Sling Therapeutics, Inc.NCT07753603

Observational

A Randomized Clinical Trial of Treating Meibomian Gland Disease in a Pediatric Population

Dry Eye Disease (DED) is commonly encountered among eye care professionals. DED is a disease of the tears and ocular surface that is multi-factorial resulting …

Dry Eye Disease, Meibomian Gland Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Illinois College of OptometryNCT07229001

Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for the Treatment of Non-arteritic Ischemic Optic Neuropathy

This trial will study the safety and efficacy of intranasal delivery of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exo…

Eye DiseasesRetinitis PigmentosaDiabetic Retinopathy+3 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05147701

Phase 4

Evaluating the Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work

This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care o…

Dry EyeEye DiseasesEyes Dry Chronic

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Southern College of OptometryNCT07266948

Phase 4

The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function

The purpose of this research study is to evaluate the effects of trehalose, an ingredient found in commercially available artificial tears, on the corneal barr…

Dry Eye Disease (DED)

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Southern California College of Optometry at Marshall B. Ketchum UniversityNCT06655441

Phase 3

A Phase III, Randomized, Double-Masked, Placebo-Controlled Study to Evaluate the Efficacy of MHB018A Injection Treatment in Subjects With Chronic Moderate-to-Severe Thyroid Eye Disease

The primary objective of this study is to evaluate the efficacy of MHB018A injection compared with placebo in participants with chronic moderate-to-severe TED.

Thyroid Eye Disease, TED

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Minghui Pharmaceutical (Hangzhou) LtdNCT07622121