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43 recruiting studies matching your filters

A Phase 2b/3, Double-masked, Randomized, Vehicle-controlled, Multicenter Study Evaluating Licaminlimab in Dry Eye Disease Patients With a Specific TNFR1 Genotype

The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of licaminlimab as compared to vehicle in p…

Dry Eye Disease (DED)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

OculisNCT07548632

Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

Objective: The objective of this study is to identify genetic causes of inherited eye conditions through whole exome or whole genome sequencing (referred to as…

Genetic Eye Disease

Estimated

~$10 – $675

Actual pay is set by the research site.

National Eye Institute (NEI)NCT02077894

Phase 2

A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled i…

Thyroid Eye DiseaseGraves OrbitopathyEndocrine System Diseases+9 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Sling Therapeutics, Inc.NCT06112340

Prospective Multicenter Observational Study for Clinical Validation of AI-Based Quantitative Eye Movement Analysis Using Smartphone-Recorded 9-Gaze Videos

This prospective, multicenter, multinational observational study evaluates the clinical validity of an AI-based quantitative eye movement analysis system (Glan…

Ocular Motility DisordersStrabismusExtraocular Muscle Dysfunction+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

THYROSCOPE INC.NCT07623837

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam l…

Thyroid Eye DiseaseGraves OphthalmopathyGraves Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Walter Reed National Military Medical CenterNCT06275373

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

The overall goal of this study is to develop Brillouin microscope as a novel tool for measuring biomechanical and hydration properties of human tissues in vivo.

Fuchs Endothelial Corneal DysfunctionOpen Angle Glaucoma (OAG)Dry Eye Disease (DED)+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT07780890

Assessment of the Ocular Microbiome in Health and Disease

The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and asse…

Microbial ColonizationEye DiseasesOphthalmopathy

Estimated

~$10 – $750

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT05414994

Phase 4

The Effectiveness of Systane PRO Preservative Free Verses Blink Triple Care Preservative Free in Providing Relief From Multiple Symptoms of Dry Eye Disease, and Its Impact on Daily Functioning and Overall Comfort in Dry Eye Subjects

The goal of this investigational study is to determine if Systane PRO Preservative Free is non-inferior to BLINK TRIPLE CARE in the clinically significant impr…

Dry Eye Disease (DED)

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Gordon Schanzlin New VisionNCT07745062

Observational

A Clinical Evaluation of the BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber in Subjects With Mild to Moderate Dry Eye Disease

The purpose of this study is to evaluate the short-term effects (impact on tear film and dry eye symptoms) of the BriTer Eyez Moisture Vue™ On-Demand Disposabl…

Dry Eye Disease (DED)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of RochesterNCT07430735

Observational

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

The goal of the current study is to conduct a pilot study to test a new version of the handheld OCT device capable of auto-alignment to image the retina in adu…

Eye DiseasesRetinal DiseaseGlaucoma+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT06841575

Phase 4

A Single Center Investigator Initiated Trial Using TRYPTYR as a Treatment for Patients With Dry Eye Disease

The purpose of this research study is to determine the effectiveness of TRYPTYR as a treatment for Dry Eye Disease. The primary efficacy variable is change fro…

Dry Eye Disease (DED)

Estimated

~$25 – $1,500

Actual pay is set by the research site.

NYU Langone HealthNCT07732010

Phase 4

Dry Eye Surveys to Evaluate Acoltremon in Real World Treatment (DESERT)

Dry eye disease (DED) is a common, chronic and multifactorial disease of the ocular surface presenting with signs and symptoms of ocular discomfort, visual dis…

Dry Eye Disease (DED)

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Center for Sight Las VegasNCT07281950