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Assessment of the Ocular Microbiome in Health and Disease
The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and asse…
Microbial ColonizationEye DiseasesOphthalmopathy
Vanderbilt University Medical CenterNCT05414994
Phase 2
Efficacy of Dapagliflozin in the Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration
AMD is a leading cause of blindness in individuals over 50 years old, with dry AMD being the most common form. Geographic atrophy (GA) is an advanced stage of …
Retinal DegenerationRetinal DiseasesEye Diseases+2 more
Washington University School of MedicineNCT07174687
Observational
Advancing Pediatric Retinal Imaging With Auto-aligned OCT
The goal of the current study is to conduct a pilot study to test a new version of the handheld OCT device capable of auto-alignment to image the retina in adu…
Eye DiseasesRetinal DiseaseGlaucoma+1 more
Duke UniversityNCT06841575
Phase 2
A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled i…
Thyroid Eye DiseaseGraves OrbitopathyEndocrine System Diseases+9 more
Sling Therapeutics, Inc.NCT06112340