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188 recruiting studies matching your filters

A Phase 2a, Randomized, Open-Label, Active-Controlled, Crossover Study to Evaluate Safety and Explore Efficacy of Different Doses of New Lipase NHS7108 Administered Orally in Participants With Exocrine Pancreatic Insufficiency- EPIC

The purpose of this study is to measure the safety and explore the efficacy of 4 different doses of the new lipase NHS7108 in participants with EPI. In this st…

Exocrine Pancreatic Insufficiency (EPI)Cystic Fibrosis (CF)Pancreatic Enzyme Abnormality+1 more

Estimated

~$10 – $8,750

Aimmune Nestlé Health Science US R&D, LLCNCT07559175

Phase 2

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Clazakizumab in Reducing hsCRP in Adults With Elevated hsCRP and Established ASCVD or at Increased Risk for ASCVD Events

The purpose of this study is to measure the change in high-sensitivity C-reactive protein (hsCRP), a marker of inflammation in the body, with clazakizumab comp…

AtherosclerosisCardiovascular DiseaseObesity+3 more

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07783802

Observational

Personalized Toolkit Building a Comprehensive Approach to Resource Optimization and Empowerment in Pregnancy & Beyond (PTBCARE+) A Randomized Controlled Trial (RCT) of Personalized Care for Prenatal Stress Reduction and Preterm Birth Disparities Prevention

The goal of this clinical trial is to learn if a personalized prenatal support program \[(Personalized Toolkit Building a Comprehensive Approach to Resource op…

Preterm Birth ComplicationPreterm BirthPreterm Birth Recurrence+19 more

Estimated

~$10 – $6,250

Phase 3

A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of VE303 for Prevention of Recurrent Clostridioides Difficile Infection

The overall objective of the RESTORATiVE303 study is to evaluate the safety and the Clostridioides difficile infection (CDI) recurrence rate at Week 8 in parti…

Clostridium DifficileClostridium Difficile InfectionsClostridium Difficile Infection Recurrence+7 more

Estimated

~$10 – $8,750

Vedanta Biosciences, Inc.NCT06237452

Efficacy of Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

Background: Systemic lupus erythematosus (SLE) is a disease that affects females nine times more often than males. People with SLE are often treated with cycl…

Systemic Lupus Erythematosus (Sle)Primary Ovarian Insufficiency (Poi)

Estimated

~$10 – $675

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT05567198

Observational

Early Feasibility Study of the DUO Transcatheter Tricuspid Coaptation Valve System in Patients With Tricuspid Regurgitation

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DUO Transcat…

Tricuspid RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease+1 more

Estimated

~$10 – $8,750

CroiValve LimitedNCT05913908

Phase 2

A Phase 2, Multicenter, Randomized, Active-controlled Study to Assess the Safety and Efficacy of ANG003 at Two Different Dose Levels in Subjects With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis

In this study, ANG003, a pancreatic enzyme replacement therapy (PERT; commonly called "enzymes"), is being investigated as a potential treatment for exocrine p…

Exocrine Pancreatic Insufficiency (EPI)Cystic Fibrosis (CF)

Estimated

~$10 – $8,750

Anagram Therapeutics, Inc.NCT07450547

Phase 3

A Phase III, Randomised, Double-blind, Study to Evaluate the Effect of Balcinrenone/Dapagliflozin Compared With Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Chronic Kidney Disease (Stage 3b and 4)

The purpose of this study is to evaluate the efficacy, safety and tolerability of balcinrenone in fixed combination with dapagliflozin, compared with dapaglifl…

Renal Insufficiency, Chronic

Estimated

~$10 – $7,500

AstraZenecaNCT07624305

Phase 2

A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE TITRATION, MULTI-CENTER STUDY TO EVALUATE THE SAFETY AND EFFICACY OF SUBCUTANEOUS MANP WHEN ADMINISTERED ONCE DAILY FOR 42 DAYS IN PARTICIPANTS WITH DIFFICULT TO CONTROL HYPERTENSION/RESISTANT HYPERTENSION

This is a Phase 2 dose-titration study designed to evaluate the safety and efficacy of MANP subcutaneous injection compared to placebo in reducing baseline day…

Difficult to Control Hypertension

Estimated

~$10 – $8,750

E-Star BioTech, LLCNCT06343298

Observational

Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study

This clinical trial is about prenatal genetic screening. It will test an intervention to help people make decisions about screening. The intervention is a shor…

Delivery of Health CareGenetic TestingHumans+9 more

Estimated

~$10 – $6,250

Case Western Reserve UniversityNCT07557303

Phase 3

Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency

Background: Premature ovarian insufficiency (POI) is a condition in which women under the age of 40 years have absent or irregular menstrual cycles. POI can c…

Premature Ovarian Insufficiency

Estimated

~$10 – $5,625

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT06851754

Medtronic Product Surveillance Registry

The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The R…

Cardiac Rhythm DisordersUrological DisordersNeurological Disorders+13 more

Estimated

~$10 – $1,125

MedtronicNCT01524276